Clinical and Experimental Pediatrics

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Improvements in obesity-related measures among Asian patients with severe obesity following a structured lifestyle intervention

Pei-Shan Chen, Shu-Mei Tsai, Chih-Hsuan Chang, Hui-Ru Yang, Yen-Ju Huang, Hsiang-Yin Liu, Kai-Chi Chang, Huey-Ling Chen

Clin Exp Pediatr. 2026;69(3):247-256. Published online December 22, 2025

Question: How does obesity severity affect baseline fitness and improvements in key obesity-related measures following participation in a structured lifestyle modification program?
Finding: Severely obese youth showed poorer baseline physical fitness but greater improvements in key obesity-related measures following lifestyle interventions.
Meaning: Early targeted intervention may help prevent progression to more severe obesity and declines in physical fitness in patients with obesity.

DOI: https://doi.org/10.3345/cep.2025.01774

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