Clinical and Experimental Pediatrics

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Hee Kyung Kang (Kang HK)

1 Article

Original Article

Polymorphisms of the NR3C1 gene in Korean children with nephrotic syndrome

Hee Yeon Cho, Hyun Jin Choi, So Hee Lee, Hyun Kyung Lee, Hee Kyung Kang, Il Soo Ha, Yong Choi, Hae Il Cheong

Clin Exp Pediatr. 2009;52(11):1260-1266. Published online November 15, 2009

Purpose : Idiopathic nephrotic syndrome (NS) can be clinically classified as steroid-sensitive and steroid-resistant. The detailed mechanism of glucocorticoid action in NS is currently unknown. Methods : In this study, we investigated 3 known single nucleotide polymorphisms (SNPs) (ER22/23EK, N363S, and BclI) of the glucocorticoid receptor gene (the NR3C1 gene) in 190 children with NS using polymerase chain reaction-restriction fragment...

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