Clinical and Experimental Pediatrics

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Hak-Ki Kim (Kim HK)

1 Article

Original Article

Effect of p16 on glucocorticoid response in a B-cell lymphoblast cell line

Sun-Young Kim, Kyung-Yil Lee, Dae-Chul Jeong, Hak-Ki Kim

Clin Exp Pediatr. 2010;53(7):753-758. Published online July 31, 2010

Crossref 1

Purpose

It has been suggested that p16 has a role in glucocorticoid (GC)-related apoptosis in leukemic cells, but the exact mechanisms have yet to be clarified. We evaluated the relationship between the GC response and p16 expression in a lymphoma cell line.

Methods

We used p16 siRNA transfection to construct p16-inactivated cells by using the B-cell lymphoblast cell line NC-37. We compared glucocorticoid...

DOI: https://doi.org/10.3345/kjp.2010.53.7.753

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