Clinical and Experimental Pediatrics

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Hae-Sook Yoo (Yoo HS)

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Case Report

A Case of Inappropriate ADH Secretion Secondary to Vinblastine Therapy

Eun-Hye Park, Hyun-Sang Cho, Hae-Sook Yoo, Chuhl-Joo Lyu, Chang-Hyun Yang, Kir-Young Kim

Clin Exp Pediatr. 1998;41(10):1430-1432. Published online October 15, 1998

Inappropriate secretion of antidiuretic hormone(ADH) secondary to vincristine therapy has been reported frequently. But there has been five previous reports of vinblastine associated SIADH in the world and in 4 reports, bleomycin and cis-platinum were used along with vinblastine together. Because penetration of vinka alkaloids into CSF of humans is known to be poor, it has been suggested that lowering...

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