- Review Article
- Growth hormone treatment and risk of malignancy
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Hyun-Wook Chae, Duk-Hee Kim, Ho-Seong Kim
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Clin Exp Pediatr. 2015;58(2):41-46. Published online February 28, 2015
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Growth hormone (GH) treatment has been increasingly widely used for children with GH deficiencies as the survival rate of pediatric patients with malignancies has increased. Both GH and insulin-like growth factor-I have mitogenic and antiapoptotic activity, prompting concern that GH treatment may be associated with tumor development. In this review, the authors examined the relationship between GH treatment and cancer... |
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- Original Article
- Effects of growth hormone treatment on glucose metabolism in idiopathic short stature
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Seung Yeon Kwon, Duk-Hee Kim, Ho-Seong Kim
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Clin Exp Pediatr. 2006;49(6):665-671. Published online June 15, 2006
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Purpose : To study the effects of growth hormone(GH) treatment on glucose metabolism and insulin resistance in children with idiopathic short stature(ISS).
Methods : Glucose and insulin concentrations were measured during oral glucose tolerance test (OGTT) before and after GH treatment(0.6-0.7 IU/kg/week) in 20 patients with ISS. Insulin resistance was assessed by homeostasis model assessment(HOMA).
Results : During OGTT, the mean... |
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