- Review Article
- Pathophysiology and management of disorders in water metabolism
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Dong Un Kim
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Clin Exp Pediatr. 2007;50(5):430-435. Published online May 15, 2007
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Even though we drink and excrete water without recognition, the amount and the composition of body fluid remain constant everyday. Maintenance of a normal osmolality is under the control of water balance which is regulated by vasopressin despite sodium concentration is the dominant determinant of plasma osmolality. The increased plasma osmolality (hypernatremia) can be normalized by the concentration of urine,... |
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- Hypernatremia and hyponatremia
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Dong Un Kim
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Clin Exp Pediatr. 2006;49(5):463-469. Published online May 15, 2006
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Sodium is the major cation of the extracellular fluid and the primary determinant of extracellular osmolality. Therefore, hypernatremia causes water movement out of cells, while hyponatremia causes water movement into cells, resulting in cellular shrinkage and cellular swelling, respectively. Serious central nervous system symptoms may complicate both conditions. Since hypernatremia and hyponatremia are accompanied by abnormalities in water balance, it... |
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- Medical Lecture Course
- Renal Transport Proteins Involved in Urinary Concentrating Mechanism
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Dong Un Kim
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Clin Exp Pediatr. 2004;47(5):480-484. Published online May 15, 2004
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Renal tubule and vasa recta are arranged in complex but specific anatomic relationships and the production of a concentrated urine is achieved by countercurrent multiplication mechanism in the renal medulla. This model requires that the ascending thin limb is highly permeable to NaCl but impermeable to water, while the descending thin limb is impermeable to NaCl but highly permeable to... |
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- Case Report
- A Case of Idiopathic Chylothorax Treated with Pleuroperitoneal Shunt
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Sung Ho Jung, Dong Un Kim, Yoon Kyung Lee, Byung Joon Choi, Jin Tack Kim, Ik Jun Lee
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Clin Exp Pediatr. 1999;42(5):733-737. Published online May 15, 1999
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Chylothorax is an accumulation of lymphatic fluid or chyle in the pleurual cavity resulting from a leak of the thoracic duct or one of its major divisions. If the loss of chyle persist, life threatening nutritional and immunologic deficiencies ensue. Initial conservative managements consist of tube thoracostomy drainage and dietary modification(low fat diet and total parenteral nutrition). In some refarctory... |
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- A Case of Marden-Walker Syndrome
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Hyun Jong Cho, Yoon Kyung Lee, Dong Un Kim, Byung Joon Choi, Jin Tack Kim, Ik Jun Lee, Je Geun Chi
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Clin Exp Pediatr. 1999;42(10):1471-1474. Published online October 15, 1999
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- A Case of Chorea in the Recovery Phase of Pneumococcal Meningitis
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Eun Ah Suh, Dong Un Kim, Yoon Kyung Lee, Bung Jun Choi, Young In Kim, Ik Jun Lee
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Clin Exp Pediatr. 1998;41(5):719-723. Published online May 15, 1998
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Movement disorders(chorea, athetosis, ballism) are a rare complication that develops during the course of bacterial meningitis although associations with tuberculous meningitis are established to some extent. Movement disorders are generally believed to reflect injury to the basal ganglia, thalamus, cerebellum and cerebral cortex. Ischemic infarctions of these areas have been proposed as the cause of dyskinesias in bacterial meningitis. We... |
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- A Case of Citrullinemia
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Dong Soo Park, Dong Un Kim, Sang Ook Park, Ik Jun Lee
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Clin Exp Pediatr. 1997;40(4):584-587. Published online April 15, 1997
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Citrullinemia is one of the five urea cycle defects and is caused by argininosuccinic acid synthetase deficiency ; conversion of citrulline to argininosuccinic acid is blocked. Severe hyperammonemia typically develops in the neonate within a few days and symptoms such as vomiting, lethargy, convulsion, coma follows rapidly. The diagnosis is supported by high citrulline level in serum, urine, CSF and... |
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- A Case of Type IV-4 Renal Tubular Acidosis
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Young A Jo, Dong Un Kim, Yoon Kyung Lee, Byung Jun Choi, Jin Tack Kim, Ik Jun Lee
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Clin Exp Pediatr. 1997;40(11):1603-1607. Published online November 15, 1997
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Type IV renal tubular acidosis(RTA) is due to renal tubular bicarbonate wasting
associated with mineralocorticoid deficiency. In its five subtypes, IV-4 is due to
pseudohypoaldosteronism(PHA) evidenced by increased plasma renin and aldosterone.
PHA is believed to result from distal tubular unresponsiveness to circulating aldosterone
and has normal renal and adrenal fuction.
Hypoaldosteronism can easily be suspected when the patient shows typical electrolyte
imbalance (hyponatremia coupled with... |
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- Original Article
- Age Related Reference Ranges for Lymphocyte Subsets in Healthy Korean Children
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Dong Un Kim, Joon Sung Lee
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Clin Exp Pediatr. 1996;39(2):264-272. Published online February 15, 1996
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Purpose : This study was aimed to investigate the age related changes of lymphocyte subset values in healthy Korean children.
Methods : Eighty healthy children were divided into four groups: group A(less than 1yr, n=20), group B(from 1 to 211/12 yr, n=20), group C(from 3 to 511/12 yr, n=20), group D(more than 6 yr, n=20). Their blood were examined for the... |
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- Case Report
- Familial Hemophagocytic Lymphohistiocytosis
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Dong Un Kim, Dae Kyun Koh, Yeon Dong Lee, Jae Kyun Hur, Kyoo Hong Cho, Suk Jin Kang
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Clin Exp Pediatr. 1994;37(9):1279-1285. Published online September 15, 1994
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Familial hemophagocytic lymphohistiocytosis (FHL) is a rare disease characterized by fever, hepatosplenomegaly, cytopenia and non-malignant lymphohistiocytic infiltration with hemophagocytosis in reticuloendothelial organs.
We experienced three cases of FHL in identical male twins and their younger brother who presented with fever and severe hepatosplenomegaly. Cytompenia, elevated serum transaminase and low serum albumin levels, hypertriglyceridemia were common laboratory findings of them. One of... |
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- Original Article
- High-Dose Intravenous Immune Globulin Therapy for Hyperbilirubinemia Caused by ABO Incompatibility
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Dong Sung Kim, Dong Un Kim, Ji Whan Han, Sung Soo Whang, Kyung Yil Lee, Man Kyu Yang
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Clin Exp Pediatr. 1993;36(8):1073-1079. Published online August 15, 1993
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Four newborn infants with hyperbilirubinemia, caused by ABO blood group incompatibility, were treated with high-dose intravenous immune globulin (IVIG).
As soon as the diagnosis was clinically suspected, these infants received conventional treatment including phototherapy and were monitored closely for bilirubin levels. When bilirubin concentrations reached the risk point in spite of pjototherapy, IVIG was given at a dose of 1g/kg for... |
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- Case Report
- A Case of Wiskott-Aldrich Syndrome
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Dong Un Kim, Seung Hoon Han, Jin Han Kang, Joon Sung Lee
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Clin Exp Pediatr. 1993;36(3):439-446. Published online March 15, 1993
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Wiskott-Aldrich syndrome s an X-linked combined immunodeficency disorder characterzed by severely decreased number of platelets which are small in size, eczema resembling atopic dermatitis and recurrent infection. The serum of the patient contains elevated concentrations of IgA and IgE, whereas the IgG level is usually normal and IgM level is deecreased. The patient also shows skin test anergy and progressive... |
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