Clinical and Experimental Pediatrics

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Original Article

Molecular Cloning and Characterization of ETV1 : a New Member of the ETS Family Transcription Factor that is Implicated in Ewing's sarcoma

In-sang Jeon, David N. Shapiro

Clin Exp Pediatr. 1999;42(6):833-843. Published online June 15, 1999

Purpose : Ewing's sarcoma is characterized by accompanying specific chromosome translocations. In the present study, we report ETV1, the third member of the human ETS family that is implicated in Ewing's sarcoma by reciprocal translocation (7;22)(p22;q12). Methods : Primarily, cDNA library made from the Ewing's sarcoma cell line accompanying the t(7;22)(p22;q12) was screened using the 5' portion of EWS(including the...

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