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Chong-Hyun Yoon (Yoon CH)

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Case Report

Two Cases of Citrullinemia Presented with Strokes

Hyun-Mi Kim, Jae-Bok Kim, Jung-Ho Kim, Sang-Jin Ba, Chong-Hyun Yoon, Han-Wook Yoo

Clin Exp Pediatr. 1999;42(3):437-441. Published online March 15, 1999

Urea cycle disorders are characterized by encephalopathy, respiratory alkalosis, and hyperammonemia. A urea cycle disorder should be considered a diagnostic possibility in any patient regardless of age with occult encephalopathy. The most common central nervous system pathology of urea cycle disorder is cerebral edema. The cerebral edema is caused by astrocyte swelling secondary to hyperammonemia and intracellular glutamine accumulation. Strokes...

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