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C U Joo

1 Article

Original Article

Morphological Study of Cardiotoxicity in Adriamycin Treated Rats.

H W Shin, J Y Kim, C U Joo, P H Hwang, J S Kim

Clin Exp Pediatr. 1989;32(8):1117-1222. Published online August 31, 1989

This experiment was carried out to investigate the morphological changes of cardiac tissue in Adriamycin treated rats. Adriamycin was administered (2.5 mg/kg/wk) for 5 weeks, subcutaneously. Cardiac tissue stained by H-E and Trichrom’s method. Clinical findings of congestive heart failure were also observed during experiment. The results were as follows ； 1) Symptoms and signs of congestive heart failure (tachypnea, ascites, hepatomegaly) were appeared in 43% (6 out...

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