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Bok Soon Kang

1 Article

Original Article

Sodium and calcium transport in spherocytic red blood cells.

Shin Heh Kang, Kir Young Kim, Young Ho Lee, Bok Soon Kang

Clin Exp Pediatr. 1991;34(7):978-991. Published online July 31, 1991

Hereditary spherocytosis (HS) is an autosomal, dominantly inherited hemolytic disorder which shows characteristic spherocytes on peripheral smear. As spherocytes are rounder, more fragile and susceptible to extravascular hemolysis in the spleen, HS patients suffer from variable degrees of anemia, jaundice, splenomegaly and gall stones. However the pathogenesis is heterogenous in HS, such as spectrin deficiency, decreased spectrin-protein 4.1 binding, increased spectrin binding to the RBC...

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