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Genetics and Metabolism

Understanding the genetics of systemic lupus erythematosus using Bayesian statistics and gene network analysis

Seoung Wan Nam, Kwang Seob Lee, Jae Won Yang, Younhee Ko, Michael Eisenhut, Keum Hwa Lee, Jae Il Shin, Andreas Kronbichler

Clin Exp Pediatr. 2021;64(5):208-222. Published online July 15, 2020

Web of Science 2 Crossref 3

Bayesian false-discovery probability and false-positive report probability are the 2 major Bayesian methods used to evaluate noteworthiness of a genetic variant.
Application of stricter P value is needed to confirm statistical significance in meta-analyses.
Gene network analysis of noteworthy genetic variants shows a blueprint of the genetic background in complex diseases.

DOI: https://doi.org/10.3345/cep.2020.00633

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