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Case Report
A Case of Castleman's Disease in Childhood
Jong Yoo Lee, Kyung Bae Park, Joon Soo Park, Sang Chul Park, Sang Man Shin, Sang Jhoo Lee, Young Moo Kyu, Ui Han Kim
Clin Exp Pediatr. 1996;39(2):291-295.   Published online February 15, 1996
Castleman's disease(CD) is rare in childhood. It is defined as a localized nodal hyperplasia in mediastinum or cervical area. It is also called angiofollicular lymph node hyperplasia, lymph nodal hamartoma, giant lymph node hyperplasia. It was first described in 1956 by Castleman et al. as a lesion of mediastinal mass. The etiology of CD is not clear. The histologic classification...
Original Article
Immunologic Considerations in the Pathogenesis of Chronic and Recurrent Sinusitis in Children
Jun Ki Jung, Bok Yang Pyun, Sang Mann Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1996;39(2):207-217.   Published online February 15, 1996
Purpose : Although the chronic sinusitis is one of the most common and troublesome respiratory diseases in children, the pathogenesis still remains unclear. It is suggested that many of the immunologic factors including allergic conditions may contribute the nasal inflammatory changes. This study was designed to evaluate and demonstrate the possible role of various immunologic factors on the pathogenesis of...
The Influence of the Use of Iodine during Perinatal Period on the Screening Test for Congenital Hypothyroidism
Gyu Bum Cho, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1996;39(2):195-206.   Published online February 15, 1996
Purpose : This study was performed to detect the diseases of congenital hypothyroidism by the neonatal mass screening test early and to demonstrate the possible role of topical iodinated antiseptics(povidone-iodine, PVP-Ⅰ) on transient hyperthyrotropinemia in newborn infants. Methods : We performed neonatal screening tests for inborn errors of metabolism since 1985 by Guthrie test for PKU, maple syrup urine disease, histidinemia,...
Serum Vitamin A Leveland Immunization Status in Serologically Confirmed Measles Patients
Kyung Hwa Park, Seung Hee Choe, Chang Hwi Kim, Dong Hwan Lee, Sang Mann Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1996;39(2):187-194.   Published online February 15, 1996
Purpose : To know the relationship between serum vitamin A level and clinical symptoms in measles patients and to re-evaluate the measles vaccination schedule, we performed this study. Methods : From Jan. to Jun. 1994, we checked serum vitamin A levels and compared with clinical symptoms, laboratory findings, complications and vaccination status in 153 patients with positive measles IgM by ELISA. Results :...
Erratum
Prevalence of Rubella Antibodies and Preventive Measures of Congenital Rubella Syndrome in Korea
Sang Jhoo Lee, Chang Hwi Kim
Clin Exp Pediatr. 1996;39(2):151-165.   Published online February 15, 1996
Original Article
Intracraial Hemorrhage in Premature and Low Birth Weight Infants by Craniosonography
Seung Hee Choi, Jae Ock Park, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1995;38(6):752-759.   Published online June 15, 1995
Purpose : Intrabventricular hemorrhage is a common neuropathologic finding in premature and low birth weight infants. It is deeply related with neonatal death and neurologic sequelae. We want to know the incidence and the relating factors of intracranial hemorrhage in premature and low birth weight infants. Methods : We performed craniosonography in 170 premature and low birth weight infants in 3-7...
Case Report
A Case of Congenital Lipoid Adrenal Hyperplasia
Hae Kyung Lee, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1995;38(4):567-573.   Published online April 15, 1995
Congenital lipoid adrenal hyperplasia is the rarest type among salt losing types of congenital adrenal hyperplasia. The defect of this disorder is in the cholesterol side chain cleavage enzyme(P450SCC)which converts cholesterol to pregnenolone. We experienced a case of 20,22 desmolse deficiency in a 21-day old phenotypically female who was admitted to our hospital due to lethargy and dark skin pigmentation. The...
A Case of Sjören-Larsson Syndrome
Kil Joon Lee, Jong Bock Kim, Dong Hwan Lee, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1994;37(12):1757-1761.   Published online December 15, 1994
Sjören-Larsson Syndrome is a rare disorder chracterized by congenital icthyosis, spastic diplegia or tetraplegia and mental retardation. The inheritance is autosomal recessive, due to deficiency of alcohol dehydrogenase activity of fatty acid matabolism. We have experienced a case of Sjören-Larsson Syndrome in a 16 month-old male children who have dried thick skin, developmental delay, and spastic diplegia. He was much improved clinically...
Original Article
Pterin & DHPR Measurement and DNA Analysis in Korean PKU Patients
Chol Hee Chong, Hye Yong Lee, Dong Hwan Lee, Sang Jhoo Lee, Ki Weon Cha, Jeong Bin Yim, Yoshiyuki Okano
Clin Exp Pediatr. 1993;36(12):1681-1690.   Published online December 15, 1993
Phenylketonuria in metabolic disorder that results from a deficiency of the hepatic phenylalanine hydroxylase. But among patients with hyperphenylalaninemia, the defect resides in one of the enzymes necessary for production or recycling of tetrahydrobiopterin (BH4). The reduction of BH4 affects not only phenylalanine metabolism but also formation of the tyrosine related neurotransmitter, dopamin and tryptophan related neurotransmitter, serotonin. Administration of L-dopa...
Intractranial Hemorrhage in Full-Term Neonates by Ultrasonography
Chang Gyu Lim, Joon Soo Park, Woo Ryong Lee, Jae Ock Park, Sang Mann Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1993;36(11):1570-1577.   Published online November 15, 1993
Intracranial hemorrhage is the most common neuropathologic finding in premature infants. But in full-term infants, It is less common and rarely causes death. We found out intracranial hemorrhages in 21 full-term neonates by real-time neurosonography and concluded as followings. 1) Among 21 neonates, 17 infants were male and 4 infants were female. 2) In 11(52.3%) infants the hemorrhage was detected within 7...
A Study of Screening for Anemia in 9 Month Old Infants in Well Baby Clinic
Yong Sik Min, Jae Ock Park, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1993;36(11):1516-1525.   Published online November 15, 1993
Iron deficiency remains the most common cause of anemia in infants and children despite increasing availability of iron-fortified foods. We screened out anemia in 9-month old infants in well baby clinic to know the prevalence of anemia and the weaning status. The results were as follows. 1) Among 345 infants screened, 24 infants(7%) were found to have anemia. 2) The king of anemia...
A Clinical Study of Histiocytosis Syndrome
Hye Yong Lee, Chul Hee Chung, Won Suk Suh, Sang Mann Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1993;36(10):1417-1425.   Published online October 15, 1993
We made a clinical study on 10 cases of histiocytosis syndrome who had been admitted to the pediatric department of Soon Chun Hyang University Hospital from Jan 1982 to Dec. 1991. The results were obtained as follows 1) The sex incidence revealed male predominance with the ratio 4:1. 2) Among 10 cases, 4 cases were classified as eosinophilic granuloma, 1 case as Letterer-Siwe...
Ultrasonographic Measurement of the Neonatal Adrenal Glands
Hae Kyung Lee, Jae Ock Park, Chang Hwi Kim, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1993;36(8):1101-1106.   Published online August 15, 1993
To determine the normal neonatal adrenal gland size, ultrasonographic examinations were performed in 145 newborn infants. They were divided into 3 groups according to the days of age. The group I is 1~3 days, group II is 6~9days and group III is 21~50days of age. 1) The adrenal gland size was as follows. In group I, the length was 29.05mm and the...
Case Report
A Case of Syndrome Associated with Colonic Atresia
Si Whan Koh, Joon Soo Park, Kyung Hwan Oh, Dong Hwan Lee, Sang Jhoo Lee, Chul Moon
Clin Exp Pediatr. 1993;36(7):1030-1033.   Published online July 15, 1993
The association of colonic atresia in patients with Down syndrome is a rare anomaly. The incidence of congenital atresia of the gastrointestinal tract has been estimated to be about one in 1500 births. Colonic atresia is rarer still, and is throut to comprise about 5% to 10% of this group. This intestinal atresia occurs in about 30% to 50% of...
A Case of Laryngeal Cleft
Yong Sik Min, Hye Kyu, Jun Soo Park, Dong Hwan Lee, Sang Jhoo Lee, Hyun Sook Hong
Clin Exp Pediatr. 1993;36(7):1016-1024.   Published online July 15, 1993
Laryngotracheoesophageal cleft is a rare congenital anomaly characterized by a midline defect of variable length between the posterior larynx and trachea and the anterior wall of the esophagus which was first reported by Richter in 1792. The male, birth weight 2780 gm, was born our hospital. After birth the infant breathed spontaneously, cried immediately but weak and did well initially but...
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