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A Study of Serologically Confirmed Measles

Journal of the Korean Pediatric Society 1992;35(4):508-514.
Published online April 15, 1992.
A Study of Serologically Confirmed Measles
Sang Mook Choi, Chang Soo Oh, Sang Chul Park, Chang Hwi Kim, Sang Jhoo Lee
Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea
혈청학적으로 진단된 홍역에 대한 고찰
최상묵, 오창수, 박상철, 김창휘, 이상주
순천향대학 의과대학 소아과학교실
Abstract
Forty one cases of serologically confirmed measles(positive measles specific IgM antibody) were evaluated among 55 cases of clinically diagnosed measles admitted to Soon Chun Hyang University Hospital from May to August 1990. The results were as follows: 1) Sex ratio was 1.6 : 1 with male predominance in 41 cases, 13 cases(31.7%) were vaccinated and 28 cases(68.3%) were unvaccinated. Primary vaccine failure was presumed to be the cause of measles in the 13 vaccinated cases(31.7%). 2) Among the 22 cases(53.7%) under 15 months of age, 14 cases(34.1%) were under 9 months of age. 3) Fever, rash and cough were noted in all of the cases, but Koplik spot was noted in only 2 9 cases. 4) The most common complication was pneumonia(68.5%). 5) Among the 55 cases of clinical measles, 32 cases were evaluated simultaneously for measles specific IgM and IgG antibodies. Measles specific IgM antibody was detected in 20 cases, with 6 cases in the vaccinated group and 14 cases in the unvaccinated group. Among the 20 cases, showing positive measles specific IgM antibody, measles specific IgG antibody was also detected in 5 of 6 cases in the vaccinated group, whereas 6 of the 14 cases in the unvaccinated group.
Key Words: Measles Specific IgM Antibody


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