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Original Article
Treatment of Acute Myelogenous Leukemia in Children: Remission Induction with Adriamycin and Cytosine Arabinoside, and Postremission Maintenance Chemotherapy with Adriamycin, Cytosine Arabinoside and 6-thioguanine.
Soon Ki Kim, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1988;31(7):850-862.   Published online July 31, 1988
The authers assessed the effectiveness of chemotherapy in 40 children with AML, experienced at Seoul National University Children’s Hospital during 8 years 5 months from April 1979 to August 1987. Remission induction treatment included adriamycin 30 mg/m2/day IV on days 1-3 and cytosine arabinoside 75 mg/m2/day continuous IV infusion on days 1-5. This regimen was repeated, if necessary, for one or two more courses. After...
Clinical Characteristics and Pathogenesis of Typhlitis in Childhood Non-Lymphocytic Leukemia-Considerations on Clinical Mangement with Report of Two Cases and Literature Review.
Do Hyun Kim, Sung Oh Kim, Soo Yup Lee, In Joon Seol, Hahng Lee, Chong Moo Park, Poong Man Jung, Seok Chol Jeon, Young Hyeh Ko, Jung Dal Lee
Clin Exp Pediatr. 1988;31(5):607-620.   Published online May 31, 1988
The treatment of acute leukemia in childhood has been increasingly successful due to progression of chemotherapeutics and other supportive care. Improved survival rates in acute childhood leukemia have been associated with an increasing number of complications in the gastrointestinal tract. Typhlitis also known as ileocecal syndrome is a necrotizing inflammation of the cecum in leukemic patients on chemotherapy in the terminal stage of the...
Burkitt Lymphoma in Children.
Soo Jong Hong, Dong Kyu Jin, Hee Young Shin, Hyo Seop Ahn, Chang Yee Hong, Je G Chi
Clin Exp Pediatr. 1988;31(4):482-491.   Published online April 30, 1988
Seventeen cases of Burkitt lymphoma under 15 years of age who were admitted to Dept, of Ped., Seoul National University Hospital from Jan. 1979 to Dec. 1986 were reviewed and analysed. One hundred and six cases of non-Hodgkin lymphoma were seen during the same period. 1) Burkitt lymphoma accounted for 16% of non-Hodgkin lymphoma. 2) The age ranged from 10/12 year to 15 5/12 years, with...
Acute Tumor Lysis Syndrome in Burkitt Lymphoma.
Dong Kyu Jin, Soo Jong Hong, Il Soo Ha, Hyo Seop Ahn, Yong Choi, Chang Yee Hong
Clin Exp Pediatr. 1988;31(3):362-369.   Published online March 31, 1988
To assess the tumor lysis syndrome in Burkitt lymphoma, we analyzed the clinical and laboratory findings of 17 patients with Burkitt lymphoma who were admitted to the Department of Pediatrics, Seoul National University Hospital from January 1979 to December 1986. The acute tumor lysis syndrome was diagnosed when two of the five following metabolic abnormal- ities were met: ① hyperuricemia (≥8.0mg/dl), ② hyperphosphatemia (≥5.5 mg/dl),...
A Case of Acute Hepatic Porphyria.
Young Cheal Han, Sin Hang Joo, Jin Han Kang, Byung Churl Lee
Clin Exp Pediatr. 1988;31(2):253-257.   Published online February 28, 1988
Acute hepatic porphyria may be an inborn error of metabolism characterized biochemically by the excessive hapatic over-production and urinary excretion of porphyrin precursors and clinically by episode of acute neuro-visceral dysfunction. Acute porphyria is very rare in childhood. We experienced a case of acute hepatic porphyria in childhood age, confirmed by characterized clinical features of neuro-visceral dysfunction and biochemical findings in blood and urine...
A Clinico-Epidemilological Study of 55 Cases of Chidhood Idiopathic Thrombocytopenic Purpura.
Won Ho Kang, Myung Hee Kook, Yong Sang Yoo, Jae Suk Ma, Tai Ju Hwang
Clin Exp Pediatr. 1987;30(11):1207-1212.   Published online November 30, 1987
Fifty-five children with idiopathic thrombocytopenic purpura (ITP) were admitted to the Department of pediatrics, Chonnam University Hospital during 6 years and 5 months from January 1980 to May 1986. We Compared clinical pictures and effects of steroids and platelet concentrates on acute and chronic ITP. No significant sexual predominance was found in total patients with ITP, but also between acute and chronic types,...
A Prospective Study ot Neonatal Acute Renal Failure: The Significance of Various Diagnostic Indices.
Kyung Hyo Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(4):378-384.   Published online April 30, 1987
Acute renal failure is defined as a sudden decrease in renal function resulting in progressive retention of nitrogenous waste products. Acute renal failure should be suspected in any infant who has a sustained decrease in urine output to less than 1 ml per kg per hour, a blood urea nitrogen level above 20 mg per dl, a serum creatinine level greater than 1.0...
Case Report
Two Cases of Nephropathy in Association with Acute Rheumatic Fever.
Young Hi Park, Myoung Su Chang, Mi Ja Yoon, Shinna Kim
Clin Exp Pediatr. 1987;30(1):102-107.   Published online January 31, 1987
Two cases of nephropathy in association with acute rheumatic fever are presented. Both patients had Rheumatic carditis with mitral valvular involvement and positive urinary laboratory findings of significant hematuria and proteinuria. There was no relapse of nephropathy after initial recovery and both patients are getting monthly injection of Benzatine-penicillin as prophylaxis to prevent recurrence of rheumatic fever.
Original Article
Studies on Type A and Type B Acute Hepatitis in Children.
Moo Young Oh, Soon Ho Kim
Clin Exp Pediatr. 1986;29(7):740-747.   Published online July 31, 1986
The author investigated incidence, age and sex distribution and some liver function tests in 128 cases of type A acute hepatitis and in 62 cases of type B acute hepatitis of children who were admitted to the pediatric ward of Busan In Je Medical college Hospital from January, 1982 to August, 1984. Diagnosis was established clinically and serologically in all patients....
A Clinical and Laboratory Study on Infection in Childhood Leukemia.
Jung Hee Lee, Kwang Hyun Kim, In Joon Seol, Heung Jae Lee, Hahng Lee, Chong Moo Park
Clin Exp Pediatr. 1986;29(7):699-709.   Published online July 31, 1986
Acute Leukemia is the most common among malignant disease in childhood, and the loss of normal hematopoiesis by proliferation of leukemic cells and the chemotherapy result in immunosuppression and the reduction of red blood cells, normal white blood cells and platelets. The children with acute leukemia may succumb to the disease due to infections, hemorrhage, other complications, or the progression...
Clinical Study of Acute Glomerulonephritis in Children.
Kyeong Rae Moon, Choon Ho Park, Sang Kie Kim, Jin Heon Kim, Chang Soo Ra
Clin Exp Pediatr. 1986;29(2):178-185.   Published online February 28, 1986
From January 1979 to June 1984, 96 cases of acute glomerulonephritis were clinically investigated at the Department of Pediatrics, Chosun University Hospital, and following results were obtained: 1) Male to female ratio was 1.7 : 1, and the age incidence was highest in children from 7 to 9 years (35.4%), with a seasonal peak in Autumn and Winter (66.8%). 2) The most common...
A Study on Four Serum Enzymes in Acute Leukemia in Children.
In Joon Seol, Seung Jae Yang, Kyoo Hwan Rhee, Hahng Lee, Chong Moo Park, Jae Kyung Koh
Clin Exp Pediatr. 1986;29(2):130-142.   Published online February 28, 1986
In order to find out whether some of serum enzyme levels could be used as markers for acute leukemia in children, activities of amylase, alkaline phosphatase, 5 -nucleotidase and ribonuclease (RNase) and positive rates of these enzymes as markers for acute leukemia in children were determined in serum of patients with acute lymphocytic leukemia (ALL) and acute non-lymphocytic leukemia(ANLL). Since the...
Serum C3 & C4 Levels and Its Clinical Significance in Acute Poststreptococcal Glomerulonephritis.
Yong Seok Lee, Kwang Su Oh, San Ho Kim, Bock Keun Kee
Clin Exp Pediatr. 1986;29(1):45-50.   Published online January 31, 1986
Acute poststreptococcal glomerulonephritis is generally known to be the most common cause of acute nephritis in children and secondary to an immunologic mechanism. esp. activating complement system. And so there have been several reports on the change of serum complement levels in the course this disease. This paper reports on observation of change of serum C3 & C4levels and its clinical significance...
A Clinical Study on Acute Appendicitis in Children.
Choong Hun Kim, Un Ki Yoon, Soon Ok Byun, Ji Sub Oh
Clin Exp Pediatr. 1985;28(12):1207-1215.   Published online December 31, 1985
This study is a clinical analysis of 225 cases of acute appendicitis in children under the age of 15 which were confirmed by operation at the department of surgery of WMBH during the past 7 year period from January 1978 to December 1984. The following results were obtained: 1)The incidence of appendicitis is rare under the age of 6 and...
Clinical Observation of Acute Viral Hepatitis in Childhood.
Byung Hak Lim, Ki Ho Jang, Sang Geel Lee, Im Ju Kang
Clin Exp Pediatr. 1985;28(11):1057-1065.   Published online November 30, 1985
A clinical observation has been made on 127 cases who were admitted to the department of pediatrics, Fatima Hospital, Taegu, from January 1983 to June 1984 and following results was obtained. 1)Ratio of male to female cases was 3 : 1. 2)On admission, anorexia, nausea, fever and jaundice were significantly more common in HBsAg negative group but skin rash was more...
Case Report
Clinical & Animal experimental observation on the Botulism Poisonig in a Family.
Yeong Du Lee, Yang Weon Lee, Jae Ho Lee, Yong Hun Chung
Clin Exp Pediatr. 1985;28(9):906-911.   Published online September 30, 1985
Five patients in a family were admitted to the department of peditrics and medicine, CNUH on July 17th, 1984 because of respiratory arrest after ingestion of the rotten sausage. All four children of five patients were expired, but only adult patient was recovered completely. Epidemiological outbreak, clinical course and animal toxin challenge test were compatible with botulism poisoning.
A Case of Acute Lymphocytic Leukemia Successfully Treated with Allogeneic Bone Marrow Transplantaion.
In Kyung Sung, Byung Churl Lee, Kyong Su Lee, Du Bong Lee, Chong Won Park, Chun Choo Kim, Dong Jip Kim
Clin Exp Pediatr. 1985;28(8):805-811.   Published online August 31, 1985
A 8-year old boy with acute lymphocytic leukemia who had shown resistance to repeated combination chemotherapies, was successfully grafted with bone marrow from his HLA- matched sister. He was in the third partial remission at the time of bone marrow transplantation. He was conditioned with cyclophosphamide 60 mg/kg/day on two consecutive days, followed by 800 rads total body irradiation. Marrow...
A Case of Acute Megakaryoblastic Leukemia.
Hye Sun Jung, Ha Baik Lee, Hahng Lee, Chong Moo Park
Clin Exp Pediatr. 1985;28(4):390-395.   Published online April 30, 1985
Acute megakaryoblastic leukemia in a very rare type of leukemia characterized by megakaryoblatic proliferation and organ infiltration without proliferation of other marrow elements. The authors experienced a case of acute megakaryoblastic leukemia in a 3 9/12 year-old female patient on admission. Acute leukemia was suspected because blast cells were found in peripheral blood smear, and there was hepatosplenomegaly. Bone marrow...
Original Article
The Use of Pedialyte(R) RS(oral electrolyte solution) and Isomil(R) in the Treatment of Nonbacterial Acute Infantile Gastroenteritis.
Keun Soo Lee, Seung Jae Yang, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1985;28(4):330-339.   Published online April 30, 1985
40 Pediatric patients with mild to moderate dehydration due to nonbacterial acute infantile gastroenteritis were admitted to the study. On admission to the hospital, each patient was assigned at random either to the Pedialyte® RS+Isomil®(Group A), or to intravenous fluid+cow's milk-based formula (Group B). Each group consisted of 20 patients. There were no significant differences between the two group as...
Case Report
A Case of Acute Febrile Mucocutaneous Lymph Node Syndrom Complicated with Ileus.
Yang Ho Park, Jin Keun Chang, Sung Sook Cho, Keun Chan Sohn
Clin Exp Pediatr. 1984;27(12):1218-1222.   Published online December 31, 1984
We experienced a case of acute febrile mucocutaneous lymph node syndrome accompanied by ileus in a 2 10/12-year-old boy. His symptoms and signs sufficed the diagnostic criteria of acute febrile mucocutaneous lymph node syndrome, and included two peaks of fever and ileus. Related literatures were reviewed briefly.
Original Article
A Clinical Observation of Acute Carbon Monoxide Poisoning.
M R Roh, K W Lee, E M Kim, S M Shin, S J Lee
Clin Exp Pediatr. 1984;27(12):1213-1217.   Published online December 31, 1984
Carbon monoxide poisoning is one of the most serious public health problem in Korea. Author analysed 126 cases of pediatric CO poisoning which had been treated in emergency room of Soon Chun Hyang Hospital, during 4 years from Jan. 1979 to Decern. 1983. The results are as follows: 1) Incidence in male was similar to that in female and the age group between 11 〜...
Decrease Serum Amylase Activity in Acutely Starvated Children with Epidemic Enephalitis.
Kyung Yong Huh, Chull Shon
Clin Exp Pediatr. 1984;27(12):1185-1191.   Published online December 31, 1984
To evaluate the effects of acute starvation on blood constituents, serum amylase activity and levels of serum urea nitrogen (BUN) and protein fractions were measured in 336 normal children and 60 children acutely starved as a result of encsphalitis. The mean starvation period was 4 days. Hypoalbuminemic children were also examined. The tests revealed that starvation resulted in a significant reduction in serum amylase...
Case Report
One Case of Neonatal Acute Lymphocytic Leukemia.
Une Hee Choi, Sang Ki Whang, In Soon Lee, In Bok Lee, Eun Cho Yang, Heum Rea Park
Clin Exp Pediatr. 1984;27(11):1103-1107.   Published online November 30, 1984
A 26 days old male with petechiae, ecchymoses and hepatosplenomegaly was admitted to the Department of Pediatrics, at In Cheon Gil Hospital on Jnue, 1983. Peripheral blood smear and bone marrow studies revealed acute lymphocytic leukemia. Autopsy findings revealed that abundant lymphoblastic leukemic cell infiltrated in bone marrow, liver, spleen, kidney and other organs in male newborn infant who died 29 days after birth. And...
Original Article
Relative Incidence of Various Acute Viral Hepatitis in Childhood.
Young Hoon Song, Gwi Jong Choi, Heung Jae Lee, Keung Soo Lee
Clin Exp Pediatr. 1984;27(6):563-569.   Published online June 30, 1984
This report was conducted to estimate the relative incidence of acute viral hepatitis (all were under 15 years of age. Who were admitted to the Pediatric Department, Hanyang University Hospital during the period from March 1982 to August 1983 were evaluated. The following results were obtained. 1)The sex ratio of of male to female was 1.34 : 1. 2)The incidence...
Reye's Syndrome in Children.
Dong Jin Lee, Sook Hee Lee, Ja Hoon Koo, Doo Hong Ahn, Yong Jin Kim
Clin Exp Pediatr. 1984;27(5):457-466.   Published online May 31, 1984
A clinical observation has been made on 44 children with Reys's syndrome who were admitted to pediatric department of KNU hospital during 6 year period from September 1977 to August 1983. Male to female ratio was 1.3 : 1. Cases under 6 years of age comprised 40(90.9%) and cases under 1 year 13(29.6%). The most common antecedent illness was URI...
Two Cases of Hemolytic Uremic Syndrome.
Sook Hee Lee, Dong Jin Lee, Ja Hoon Koo, Doo Hong Ahn, Young Jin Kim
Clin Exp Pediatr. 1984;27(4):384-389.   Published online April 30, 1984
The hemolytic uremic syndrome is a clinical state characterized by uremia, thrombocytopenia and microangiopathic hemolytic anemia. Since the first description of this illness by Gasser in 1955, it has been recognized with increasing frequency. Recently, we have experienced 2 cases of severe hemolytic uremic syndrome occurring in boys in 5 and 6 years of age. Diagnosis was established by typical...
Clinical Observation of Acute Lymphocytic Leukemia with Mediastinal Mass.
In Sil Lee, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1984;27(4):343-349.   Published online April 30, 1984
Twenty four cases of acute lymphocytic leukemia with mediastinal mass were studied at the Department of Pediatrics, Seoul National University Hospital from September 1965 to August 1983. Analysis were done with regard, to age, sex, chief complaints, organ size (liver, spleen and lymph nodes), initial hemoglobin, white blood cell and platelet count, initial bone marrow findings and lymphoblast surface markers....
Case Report
Korean Hemorrhagic Fever in Children.
Won Seok Lee, Yong Hoon Park, Ja Hoon Koo, Doo Hong Ahn, Yong Jin Kim
Clin Exp Pediatr. 1984;27(3):265-270.   Published online March 31, 1984
Korean hemorrhagic fever is acute febrile illness caused by Hantan virus. It involves capillaries and small vessels systemically, and leads to dysfunctions of many organs, esp. kidney. In recent years, we have experienced 4 cases of korean hemorrhagic fever in children’s age group. Diagnosis was confirmed by immunofluorescent technique in one case and renal biopsy was done in 2 cases....
Original Article
Acute Renal Failure in Children.
Chan Lak Son, Sun Hwan Chung, Yong Hoon Park, Kuhn Soo Lee, Ja Hoon Koo
Clin Exp Pediatr. 1984;27(2):146-155.   Published online February 28, 1984
A clinical study was conducted on 76 children with acute renal failure who had been admitted to the Pediatric Department of Kyungpook National University Hospital during 2.2years period from January 1981 to June 1983, and following results were obtained.Age distribution revealed 19 out of total 76 cases (25%) being infants under 1 year of age and otherwise even distribution was...
Case Report
A Case of Acute Lymphocytic Leukemia with Both Renal Enlargement.
Bok Hee Oh, Young Hoon Soung, Woo Gill Lee, On Koo Cho
Clin Exp Pediatr. 1983;26(11):1149-1153.   Published online November 30, 1983
A Case of acute lymphocytic leukemia with both renal enlargement found l^year old female has been presented. After treatment , acute lymphocytic leukemia with chemotherapeutic agent, the size of both kidneys were decreased and returned to normal shape by ultrasonogram series. A brief review of the literature was made on this subject.
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