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Serum C3 & C4 Levels and Its Clinical Significance in Acute Poststreptococcal Glomerulonephritis.

Journal of the Korean Pediatric Society 1986;29(1):45-50.
Published online January 31, 1986.
Serum C3 & C4 Levels and Its Clinical Significance in Acute Poststreptococcal Glomerulonephritis.
Yong Seok Lee, Kwang Su Oh, San Ho Kim, Bock Keun Kee
Department of Pediatrics, Wonkwang University, School of Medicine, Iri. Korea
소아 급성 사구체신염에서 혈청 C3, C4,치의 변화와 그 임상적 의의
이용석, 오광수, 김산호, 기복근
원광대학교 의과대학 소아과학교실
Abstract
Acute poststreptococcal glomerulonephritis is generally known to be the most common cause of acute nephritis in children and secondary to an immunologic mechanism. esp. activating complement system. And so there have been several reports on the change of serum complement levels in the course this disease. This paper reports on observation of change of serum C3 & C4levels and its clinical significance in 50 cases of poststreptococcal glomerulonephritis who were admitted in department of pediatrics. Wonkang University Hospital. from April 1984 to March 1985. The results as follows: 1) Comparing with control group. initial serum C3 levels were markedly reduced in most of cases and initial serum C4 levels were also reduced in some of cases but to lesser extent (P
Key Words: Acute poststreptococcal glomerulonephritis, Serum C3 & C4 levels.


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