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Original Article
Serum Lipids and Fatty Acids According to the Type of Feeding in Children
Kyung Hwan Oh, Jae Ock Park, Chang Hwi Kim, Sang Mann Shin
Clin Exp Pediatr. 1997;40(8):1098-1103.   Published online August 15, 1997
Purpose : Lipids and fatty acids are very important for brain and nervous system in growing children. This study was carried out to compare the composition of serum lipids and fatty acids according to the type of feeding in children. Methods : One hundred and twenty two children aged from 5 month to 24 month who visited Soonchunhyang University Hospital from Mar. 1995 to...
The Concentration of Insulin Like Growth Factor-I(IGF-I) and IGF-Binding Protein-3 (IGFBP-3) in the Serum of Children with Growth Hormone Deficiency and the Alterations after Growth Hormone Treatment
Woo Yeong Chung, Dae-Yeol Lee
Clin Exp Pediatr. 1996;39(6):846-855.   Published online June 15, 1996
Purpose : The insulin like growth factors (IGFs) circulate complexed to IGF-binding proteins(IGFBPs). IGFBP-3 is the major circulating IGFBP and is found primarily as a 150 kDa complex which contains an acid labile subunit(ALS), IGFBP-3, and IGF-I or IGF-II and is considered to be growth hormone(GH) dependent. In this study, we measured serum IGF-I, IGFBP-3 and 150 kDa levels in sera of growth hormone...
Serum IgE Standardized for Age in Korean Children and Its Diagnostic Reliability in Childhood Asthma
Myung Su Lee, Eun Sun Yoo, Hye Sun Kim, Eun Ae Park, Jeong Wan Seo, Seung Joo Lee
Clin Exp Pediatr. 1996;39(3):397-403.   Published online March 15, 1996
Purpose : IgE was identified by Ishizaka as an antibody that is reacted at Type I hypersensitivity reaction, and has been used in the diagnosis of allergic disease and the differential diagnosis of extrinsic and intrinsic asthma. But there was some confusing in the diagnosis because of the broad range of measured serum IgE. Recently it was reported that serum IgE...
Serum Lipids in Children and Adolescents with Family History of Coronary Artery Diseases
Kee Hyoung Lee, Chang Sung Son, Joo Won Lee, young
Clin Exp Pediatr. 1995;38(4):482-492.   Published online April 15, 1995
Purpose : Atherosclerotic change begins in childhood, elevated blood lipid levels and a family history of premature coronary vascular diseases are important risk factors for coronary artery disease. Identification, follow-up and treatment of children at high risk of cardiovascular diseases are very effective and important for prevention of future coronary artery diseases. The purpose of this study is to determine...
A Study of Relation between Serum Aminotransferase Elevation and Clinical Symptoms from Human Rotavirus Gastroenteritis
Gee Sun Hong, Hwa Young Jeon, Won Kyu Choi, Mee Kyung Namgoong, Jong Soo Kim
Clin Exp Pediatr. 1995;38(1):54-60.   Published online January 15, 1995
This study was taken to measure the serum aminotransferase level and it's correlation with clinical symptoms from Human Rotavirus gastroenteritis. This report is based on analysis of 434 patients who were admitted to the Pediatric department at Wonju Christian Hospital because of watery diarrhea and vomiting during 2-year period from July, 1991 to June 1993. The stool specimen on admission...
A Study on the Serum Triglyceride Values in Children
Sang Won Cha, Young Hun Chung
Clin Exp Pediatr. 1994;37(11):1519-1525.   Published online November 15, 1994
The concentration of serum triglyceride values were studied at department of pediatrics, Chungnam National University Hospital. With the total 742 cases, among them 462 boys and 280 girls who were at the age of 2 months through 15 years old. Serum triglyceride values were measured to determine the distribution of values and evaluated on the basis of sex, age, height...
A Study on Serum Immunoglobulins and Complements in Newborn Infants by Gestational Weeks
Ji Eun Lee, Kyung Hyo Kim, Kyung Hee Kim
Clin Exp Pediatr. 1993;36(11):1555-1561.   Published online November 15, 1993
The author investigated serum immunoglobulin (IgG, IgA, and IgM) and complements (C3) of cord blood in 74 cases of normal fulterm infants and 50 cases of premature infants. Serum immunolglobulin and complement levels were measured by the single radial immunodiffusion method. The following results were obtained ; 1) The mean serum IgG levels of cord blood in 74 cases of the normal...
A Study of Serum Transaminase Level and It's Correlation with Several Symptoms in Children with HRV Gastroenteritis
Gang Youl Bae, Eui Tak Oh, Woo Sik Jung, Kil Seo Kim
Clin Exp Pediatr. 1993;36(8):1146-1155.   Published online August 15, 1993
The retrospective study was taken to study the serum trasnsaminase level and it's correlation with several symptoms in human rotavirus gastroenteritis. 494 children, who admitted to the Department of Pediatrics in Dae Dong Hospital from January 1991 to December 1991 with chief complaints of waterdy diarrhea were included in studies. The 1 st stool specimen on admission was tested for rotavirus Ag...
Serum Alkaline Phosphatase Activity after Intravenous Administration of Albumin Preparation
June Huh, Kang Mo Ahn, Ja Wook Koo, Il Soo Ha, Hae Il Cheong, Yong Choi
Clin Exp Pediatr. 1993;36(6):830-836.   Published online June 15, 1993
Serum alkaline phosphatase(AP) activity is elevated in hepatobiliary disease, bone disease, pregnancy and certain neoplasms. Recently we experienced marked elevation of serum AP activity after administration of ablumin preparation in nephrotic patients who suffered from hypovolemic symptoms. So serum AP activity and the isoenzymes in the albumin preparations & patient뭩 serum after the administration of albumin preparation were studied. Serum...
A Study of Serum CK-BB Activity as a Diagnostic Method and a Predictor of Neurologic Out come in Asphyxiated Infants
Clin Exp Pediatr. 1993;36(3):371-378.   Published online March 15, 1993
Asphyxia is the most important perinatal cause of neurologic morbidity in infants. Recently, elevated levels of CK-BB have been demonstrated in serum after asphyxic insult in infants. To evaluate the possibility of using serial measurements of CK-BB activity as a diagnostic method and a predictor of neurologic outcome in asphyxiatic infants. We studied CK-BB activity in serum of asphyxiated infants(16...
The Side Effects of Antiepileptic drugs in Epileptic Children Treated withMonotherapy
Kon-Hee Lee, Hae-Sun Yoon
Clin Exp Pediatr. 1993;36(3):320-327.   Published online March 15, 1993
The goal of therapy of epileptic children is to control of seizures with minimal side effects of antiepileptic drug(AED). The relationship between side effects, serum levels and doses of AED were examined prospectively in 72 epileptic children who received monotherapy with phenobarbital, phenytoin, valproate, or carbamazepine for 6 to 26 months. Our results were as follows: 1) Side effects were observed in...
The Study of Serum Lipids in Grossly Obese Elementary School Students in Seoul
Seong Hang Choi, Kyoung Bum Kim, Se Geun Park, Ji Tae Chung, Chang Sung Son, Young Chang Tockgo
Clin Exp Pediatr. 1993;36(1):73-80.   Published online January 15, 1993
Our study surveyed 418 obese first grade elementary school children (279 male and 139 female), in seoul, and measured levels of serum total cholesterol, HDL Cholesterol, LDL cholesterol, triglyceride were measured in addition to the measurement of body weight and height. The following results were obtained. 1) Obesity index was catergorized into mild, moderate, and severe, and the percentage of mild was...
A Clinical Study on Duchenne Muscular Dystrophy
Moon Sun Yang, Su Ahn Chae, Ki Joong Kim, Yong Seung Hwang
Clin Exp Pediatr. 1992;35(5):652-658.   Published online May 15, 1992
Twenty-five cases of Duchenne muscular dystrophy(DMD) who were diagnosed in the department of pediatrics, Seoul national university hospital (from Jan. 1985 to June 1991) were reviewed. The results were as follows. 1) All of the patients were male. 2) The onset of symptoms was between two and eight years of age. The peak incidence was at four years of age. 3) Chief complaints...
A Study of Calcium and Inorganic Phosphorus Levels in Maternal and Cord Blood
Woo Ha You, Seung Wan Lee, Jong Lin Rhi, Hyun Joo Jeong, Yong Joon Shin, Chung Hak Park
Clin Exp Pediatr. 1992;35(4):492-498.   Published online April 15, 1992
A study of serum calcium, phosphorus levels in mother and umbilical cord was carried on 39 mother/baby pairs who were admitted to DAE HAN Hospital from Nov.1989 through Feb.1990. The results abstained were as follows: 1) The mean serum calcium levels of maternal and cord blood were 8.92¡¾10.59mg% and 9. 88¡¾10.74mg% repectively. The mean serum calcium of cord blood was statiscally higher than...
A Study of Serum Transaminase Level and It's Correlation with Dehydration in Children with HRV Gastroenteritis.
Tae Joon Park, Eung Sang Choi
Clin Exp Pediatr. 1990;33(12):1662-1669.   Published online December 31, 1990
The study was taken to study the serum transaminase level and it’s correlation with dehydration in Human Rotavirus gastroenteritis. 129 children, who admitted to the Department of Pediatrics in Chung-Ang University Hospital from January 1987 to December 1989 with chief complaints of fever, vomiting, and watery diarrhea were included in this studies. The stool specimen on admission was tested for Rotavirus Ag by ELISA method....
Serum Ribounclease Activity in Patients with Leukemia and Chromatographic Isolation of the Enzyme.
Young Suk Koh, Keun Lee
Clin Exp Pediatr. 1989;32(12):1715-1725.   Published online December 31, 1989
In order to find out the possibility for using serum ribonuclease (RNase) activity as diagnostic and therapeutic markers for leukemia, serum neutral, acid and alkaline RNase activities were determined in patients with acute lymphocytic leukemia (ALL) before and after anticancer therapy and in patients with acute myelogenous leukemia (AML). Also, serum RNases (neutral, acid and alkaline (RNase)and proteins were analyzed by column...
A Trend of Serum C3 and C4 levels in Acute Poststreptococcal Glomerulonephirtis.
Dong Seok Choi, Young Hun Chung
Clin Exp Pediatr. 1989;32(7):965-971.   Published online July 31, 1989
Acute poststreptococcal glomerulonephritis is generally stated to be the most common cause of acute nephritis in childhood and secondary to an immunologic mechanism. In acute poststreptococcal glomerulonephritis, there have been several reports on the change of serum complement levels in the course of disease. This paper reports on observation of change of serum C3 & C4 levels and its clinical significance in 41 cases of...
Serum IgE Level in Patients with Minimal Change Nephrotic Syndrome.
Sung Oh Kim, Hee Jung Ahn, Seong Ho Kim, Woo Gill Lee
Clin Exp Pediatr. 1989;32(6):789-796.   Published online June 30, 1989
It has been reported that many patients with minimal change nephrotic syndrome(MCNS) have high serum IgE level, but its significance has not been disclosed yet. In this study, serum levels of IgE were evaluated in different stages of the disease with or without treatment in 26 MCNS(proven by renal biopsy) patients admitted to the Department of Pediatrics Hanyang University Hospital from January, 1980 to...
Predictive Capacity of Cord Serum IgE for Developement of Atopy.
Hye Ran Byun, Hye Won Lee, Keun Lee
Clin Exp Pediatr. 1989;32(3):390-395.   Published online March 31, 1989
The incidence of atopic disease has increased in recent years and its symptom begins early in life, in many cases during the first year. It is desirable, therefore, to predict the development of atopic disease early in infancy, preferably in neonatal period, so that it can be prevented or, at least, lessened in symptoms by proper management. One hundred and two fullterm newborn...
Relationship of Maternal and Cord Serum Ferritin.
Hae Sung Cho, Jin Hyun Park, Hee Jung Kwon, In Sil Lee
Clin Exp Pediatr. 1988;31(11):1453-1459.   Published online November 30, 1988
There is controversy as to whether maternal serum ferritin level influences the level of ferritin in the cord blood serum of newborns or not. The present study was designed to evalulate the influence of iron storage status of mothers on the newborn infant. Paired samples from 51 uncomplicated pregnant women and their newborns who were admitted to the department of OB & GY, National...
Iron Deficiency Anemia in Childhood and Diagnostic Significance of Serum Ferritin.
Dong Hyub Lee, Ki Hong Park, Kyu Chul Choi, Yong Mook Choi
Clin Exp Pediatr. 1988;31(5):577-583.   Published online May 31, 1988
In order to elucidate clinical and laboratory findings of the iron deficiency anemia(IDA) in childhood along with diagnostic significance of serum ferritin, 207 patients were analyzed retrospec- tively, who were hospitalized at Department of Pediatrics, Kyung Hee University Hospital from January 1981 to December 1986. The results were as follows; 1) The incidence of IDA in In-Patient was 1.6%. 2) The sex ratio of male to female was...
A Study on Serum Ca, P, Mg, Parathyroid Hormone, Calcitionin, and 1, 25-dihydroxyvitamin D Concentrations in Normal Newborn and Low Birth Weight Infants.
In Bock Lee, Chang Soo Ra
Clin Exp Pediatr. 1987;30(6):613-624.   Published online June 30, 1987
Early neonatal hypocalcemia occurs within the first few days of life, with the lowest concentrations of serum calcium being reached at 24 to 48 hours of age. An infant can be considered to be hypocalcemic when serum calcium concentrations are below 7 mg/dl or when ionized calcium concentrations are below 3 to 3.5 mg/dl. The most commonly encountered causes of neonatal hypocalcemia are prematurity,...
Continuous Intravenous Glucose Infusion and Serum Glucose in Neonates.
Hae June Park, Jung sik Rhim, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1987;30(5):499-503.   Published online May 31, 1987
Serum glucose changes by constant infusion of glucose at the rate of 8 mg/kg/min were studied in 20 neonates. Serum glucose level elevated from 41 ±8 mg/dl to 80 ±31 mg/dl within 10 minutes of infusion. In some cases hyperglycemia above 150 mg/dl was observed from 40 minutes of infusion. Constant glucose infusion was found to be useful for elevation of glucose level...
Postnatal Changes of Serum Creatinine Levels in Neonates.
Jeong Wan Seo, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1986;29(9):948-953.   Published online September 30, 1986
The concentration of creatinine, one of the simple and commonly used indices of glomerular filtration rate in children and adults, has been reported to be appreciably raised and variable during the first month of life. This study examined the effect of gestational age(G.A.) on the postnatal changes of creatinine in preterm and full-term neonates. The results were as follows; 1) The mean...
A Study on Plasma Antidiuretic Hormone and Serum Sodium Levels of Cord Blood in the Newborn Infants.
Choon Ho Park, Chang Soo Ra
Clin Exp Pediatr. 1986;29(7):748-757.   Published online July 31, 1986
The authors studied the plasma antidiuretic hormone levels of cord blood in 40 cases of newborn infants and also studied the serum sodium levels of cord blood in 40 cases of newborn infants. For the purpose of analysis, the study subjects were divided into four group; 1st group of 17 cases of vaginal delivery infants with fetal distress, 2nd group...
A Comparative Study on Serum Ferritin Concentrations in Anemic Patients Various Diseases.
Sei Woo Chung, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1986;29(7):730-739.   Published online July 31, 1986
Ferritin is a high-molecular weight iron compound consisting of a protein shell, which has normally been considered as a storage compound from which iron is readily mobilized either into the transferrin-bound plasma pool or for intracellular heme synthesis. For comparison of serum ferritin concentrations in anemic patients of various diseases, we measured serum ferritin concentrations, serum iron concentrations, total iron...
A study on Serum Calcium, Phosphorus, Magnesium and Parathyroid Hormone Levels of Cord Blood in Newborn.
Kwang Rhun Koo, Chang Soo Ra
Clin Exp Pediatr. 1986;29(2):163-169.   Published online February 28, 1986
A study of serum calcium, magnesium, phosphorus and PTH levels of cord blood in newborn infants and those of serum levels of maternal blood at parturition was carried on 38 mother/baby pairs who were admitted to Chosun University Hospital from November, 1982 throgh Desember, 1982. The following results were obtained; 1) The serum calcium levels of cord blood in 38 cases of the...
A Study on Serum Immuoglobulins and Complements in Newborn Infants.
Song Soo Moon, Chang Soo Ra
Clin Exp Pediatr. 1986;29(1):58-71.   Published online January 31, 1986
The author investigated serum immunoglobulins (IgG, IgA, and IgM) and complements (C3and C4) of cord blood in 29 cases of normal fullterm infants, 14 cases of low birth weight infants (8 cases of premature infants) and 43 cases of their mothers at delivery. Serum immunoglobulin and complement levels were measured by the single radial immuno diffusion method (NISSUI, Japan). The...
Serum C3 & C4 Levels and Its Clinical Significance in Acute Poststreptococcal Glomerulonephritis.
Yong Seok Lee, Kwang Su Oh, San Ho Kim, Bock Keun Kee
Clin Exp Pediatr. 1986;29(1):45-50.   Published online January 31, 1986
Acute poststreptococcal glomerulonephritis is generally known to be the most common cause of acute nephritis in children and secondary to an immunologic mechanism. esp. activating complement system. And so there have been several reports on the change of serum complement levels in the course this disease. This paper reports on observation of change of serum C3 & C4levels and its clinical significance...
A Study on Changes of Serum Prootein, Immunoglobulins, and Electrolyte Metabolism in Childhood Nephrotic Syndrome after Steroid Therapy.
Kyung Rae Moon, Chang Soo Ra
Clin Exp Pediatr. 1986;29(1):32-44.   Published online January 31, 1986
The author determined serum and 24hr urine protein(total protein and albumin), immunoglobulins(lgG, IgA, and IgM) and serum electrolytes(Na, K, Ca, P, Mg, and Cl) in 5 cases of childhood nephrotic syndrome before and after steroid therapy, until urinary excretion of protein was negative (remission).The results observed are summarized as follows; 1) Serum protein; Before treatment, the mean serum total protein...
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