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Original Article
Log-transformed plasma level of brain natriuretic peptide during the acute phase of Kawasaki disease is quantitatively associated with myocardial dysfunction
Sunhee Bang, Jeong Jin Yu, Myung-Ki Han, Hong Ki Ko, Sail Chun, Hyung Soon Choi, Young-Hwue Kim, Jae-Kon Ko, In-Sook Park
Clin Exp Pediatr. 2011;54(8):340-344.   Published online August 31, 2011
Purpose

Brain natriuretic peptide (BNP) has been considered a biochemical marker for myocarditis in Kawasaki disease. We performed this study to determine its quantitative significance.

Methods

We attempted to correlate log-transformed BNP concentrations (log-BNP) and clinical, laboratory, and echocardiographic variables in 81 children with Kawasaki disease. Stepwise multiple linear regression analysis was used to determine the variables independently associated with log-BNP concentration.

Results

Serum C-reactive...



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