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Original Article
Alteration of CD4+CD25+Foxp3+ T cell level in Kawasaki disease
Su Ye Sohn, Young Wooh Song, Yun Ku Yeo, Yun Kyung Kim, Gi Young Jang, Chan Wook Woo, Jung Hwa Lee, Kwang Chul Lee
Clin Exp Pediatr. 2011;54(4):157-162.   Published online April 30, 2011
Purpose

Exaggerated pro-inflammatory reactions during the acute phase of Kawasaki disease (KD) suggest the role of immune dysregulation in the pathogenesis of KD. We investigated the profiles of T regulatory cells and their correlation with the clinical course of KD.

Methods

Peripheral blood mononuclear cells were collected from 17 KD patients during acute febrile and subacute afebrile phases. T cells expressing CD4, CD25,...

Case Report
A childhood case of spinal tuberculosis misdiagnosed as muscular dystrophy
Doo Il Song, Su Ye Sohn, Yun Kyung Kim, So Hee Eun, Young Jun Rhie, Gi Young Jang, Chan Wook Woo, Byung Min Choi, Jung Hwa Lee, Bo Kyung Je
Clin Exp Pediatr. 2010;53(5):657-660.   Published online May 31, 2010

Tuberculosis is primarily a pulmonary disease, but extra-pulmonary manifestations are not uncommon, especially in children and adolescents. Ten percent of extra pulmonary tuberculosis localizes to the bones and joints, and 56% of such cases affect the spine. We treated a childhood case of spinal tuberculosis misdiagnosed as muscular dystrophy in a patient without specific constitutional symptoms. We report this case...

Original Article
Evaluating and managing hypertension in children: a survey of Korean cardiologists and nephrologists
Eun Hee Lee, Hyung Eun Yim, Gi Young Jang, Kee Hwan Yoo, Chang Sung Son, Young Sook Hong, Joo Won Lee
Clin Exp Pediatr. 2008;51(9):992-997.   Published online September 15, 2008
Purpose : Hypertension (HTN) is no longer an exclusively adult disease; the prevalence of pediatric HTN is increasing. To understand the evaluation and treatment of childhood HTN in Korea, we investigated, via a questionnaire, how hypertensive children are currently assessed and managed by pediatric cardiologists (CA) and nephrologists (NE). Methods : We surveyed 82 pediatric CA and 77 NE, regarding...
Review Article
Cardiovascular complications after Kawasaki disease and its management
Gi Young Jang
Clin Exp Pediatr. 2008;51(5):462-467.   Published online May 15, 2008
Kawasaki disease is a systemic vasculitis of unknown etiology, usually occurring in infants and young children. Although the etiology of Kawasaki disease remains uncertain, its serious complicationssuch as giant aneurysm formation, coronary arterial stenotic lesions, and thrombotic occlusionhave been proven to cause myocardial ischemia or infarction in patients with Kawasaki disease. To prevent and treat these complications, several modes of...
Original Article
Complications of transcatheter closure of atrial septal defects using the amplatzer septal occluder
Seo Jin Jea, Hyo Jin Kwon, Gi Young Jang, Jae Young Lee, Soo Jin Kim, Chang Sung Son, Joo Won Lee
Clin Exp Pediatr. 2008;51(4):401-408.   Published online April 15, 2008
Purpose : Transcatheter closure of atrial septal defects (ASD) is currently established therapy as an alternative to surgery. But rarely, complications are reported in some studies. We report early and intermediate term complications associated with transcatheter closure of atrial septal defects using the Amplatzer septal occluder (ASO). Methods : From June 2003 to May 2006, 64 patients underwent transcatheter closure of...
Case Report
Perforation of azygos vein and right-sided hydrothorax caused by peripherally inserted central catheter in extremely low birth weight infant
Kee Soo Ha, Jung Yeon Shin, Mi Jung Hwang, Young Ok Choi, Dong Han Shin, Gi Young Jang, Byung Min Choi, Kee Hwan Yoo, Young Sook Hong, Chang Sung Son
Clin Exp Pediatr. 2006;49(8):902-905.   Published online August 15, 2006
We report a case in which routine chest roentgenograms of an 840 g infant led to the belief that the peripherally inserted central catheter (PICC) was appropriately positioned within the superior vena cava when, in actuality, it was within the azygous arch. Although many cases of pleural effusions have been reported to be caused by a central venous catheter, a...
A case of constrictive pericarditis presenting with protein-losing enteropathy
Jeong Mi Hong, Jae Young Lee, Soo Jin Kim, Gi Young Jang, Woo Sup Shim
Clin Exp Pediatr. 2006;49(8):898-901.   Published online August 15, 2006
Constrictive pericarditis represents a rare cause of protein-losing enteropathy in children. Reported is an 11-year-old girl with protein-losing enteropathy (PLE) as the principal manifestations of constrictive pericarditis. After total pericardiectomy, symptoms and signs of PLE disappeared. Doppler echocardiography including tissue Doppler imaging is a useful noninvasive initial diagnostic tool for differential diagnosis of diastolic heart failure.
Original Article
N-terminal Pro-B-type Natriuretic Peptide as a Predictive Risk Factor in Fontan Operation
Gi Young Jang, Jae Young Lee, Soo Jin Kim, Woo Sup Shim
Clin Exp Pediatr. 2005;48(12):1362-1369.   Published online December 15, 2005
Purpose : This study aimed to investigate the correlation between the plasma level of N-terminal pro-B-type natriuretic peptide(pro-BNP) and several known risk factors influencing outcomes after Fontan operations, and to assess whether pro-BNP levels can be used as predictive risk factors in Fontan operations. Methods : Plasma pro-BNP concentrations were measured in 35 patients with complex cardiac anomalies before catheterization....
Follow-up in Adult after Total Repair of Tetralogy of Fallot
Gi Young Jang, Sun Young Kim, Joo Ryung Moon, Joon Huh, I-Seok Kang, Seung Woo Park, Tae Gook Jun, Pyo Won Park, Heung Jae Lee
Clin Exp Pediatr. 2003;46(7):661-667.   Published online July 15, 2003
Purpose : This study was performed to find the chief clinical problems associated with the ages of adult patients of tetralogy of Fallot(TOF) who had undergone total correction. Methods : Of the 30 patients who were registered at the Grown-Up Congenital Heart Disease (GUCH) Clinic of Samsung Medical Center for TOF, a retrospective investigation was carried out on 28 patients who...
Predisposing Factors of Risk Taking Behaviors in Korean Adolescents
Jae Hee Soh, Yeon Kyeong Jung, Gi Young Jang, Young Kyoo Shin, Kee Hyoung Lee, Baik Lin Eun, Sang Hee Park
Clin Exp Pediatr. 2001;44(12):1364-1373.   Published online December 15, 2001
Purpose : Risk-taking behaviors are defined as patterns of behavior initiated during adolescence which are responsible for the majority of negative health outcomes occurring during the rest of the life. The study was to explore the relationship between the risk-taking behaviors and their predisposing factors among adolescents. Methods : The study used a survey design with an anonymous self-report questionnaire administered to 1,076 students from...
The Role of Aldosterone on the Development of Renal Tubular Reabsorption in Low Birth Weight Infants
Byung Min Choi, Hoe Kyoung Koo, Jin Won Yook, Kyoung Bum Kim, Gi Young Jang, Moon Hee Kim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 2001;44(11):1233-1242.   Published online November 15, 2001
Purpose : To determine the postnatal changes in aldosterone action on the renal tubular reabsorption in low birth weight(LBW) infants, we assessed the relation of the aldosterone concentrations to renal parameters during the first 10 days of life. Methods : Twenty LBW infants were evaluated and their gestational ages ranged from 32.4 to 39.3 weeks and their birth weights ranged from...
Measles, Mumps, and Rubella Immunization in Children with Egg Allergies
Seung Yeon Nam, Eun Hee Jung, Jin A Jung, Yong Min Park, Kyoung Hee Jeon, Ju Suk Lee, Gi Young Jang, Kang Mo Ahn, Sang Il Lee
Clin Exp Pediatr. 2001;44(9):1031-1035.   Published online September 15, 2001
Purpose : The safety of MMR(Measles, Mumps, and Rubella) immunization to children with egg allergies has been debated for decades because the live attenuated virus used in the vaccine is grown in cultured chick-embryo fibroblasts. Many studies that investigated adverse reactions to MMR vaccine have been reported abroad, but there has been no report in Korean children. So, this study is aimed at determining...