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Case Report

A Case of Congenital Insensitivity to Pain with Anhidrosis

Munhyang Lee, Nam Seon Beck, Dongkyu Jin, Yeon-Lim Suh

Clin Exp Pediatr. 1997;40(11):1621-1626. Published online November 15, 1997

Congenital insensitivity to pain with anhidrosies (CIPA) is one of the exceedingly rare hereditary sensory autonomic neuropathies (HSAN). There are five types of HSAN according to hereditary transmission, natural history, clinical manifestations, and pathologic findings. The CIPA corresponds to type IV and is characterized by episodes of recurrent fever with generalized anhidrosis, insensitivity to pain and temperature with self-multilation, and mental retardation. We report a 14...

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