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Original Article

Changes in Somatostatin Immunoreactive Neurons in Rat Corebral Cortes after Systemic Kainic acid Administration

Myung Yeun Lee, Sa Jun Chung, Chang Il Ahn

Clin Exp Pediatr. 1993;36(9):1279-1290. Published online September 15, 1993

This study was aimed to clarify the effects of systemic kainic acid(KA) administration(10mg/kg i.p.) on somatostatin containing neurons, and to examine the distribution of somatostain immunoreactive neurons in the cerebral cortex of the rats. Animals were sacrificed at three time points at the two, six, and ten days after the injection of KA. Thirty-six rats were observed by using the free-floating immunohistochemical...

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