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Nephrology (Genitourinary)

Atypical hemolytic uremic syndrome and eculizumab therapy in children

Seong Heon Kim, Hye Young Kim, Su Young Kim

Clin Exp Pediatr. 2018;61(2):37-42. Published online February 28, 2018

Crossref 5

Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing Escherichia coli-associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has been studied recently. aHUS is a rare, chronic, and devastating disorder that progressively damages systemic organs, resulting in stroke, end-stage renal disease, and death. The traditional treatment for aHUS is...

DOI: https://doi.org/10.3345/kjp.2018.61.2.37

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