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Review Article

Neonatology (Perinatology)

Pathophysiology, classification, and complications of common asymptomatic thrombocytosis in newborn infants

Ga Won Jeon

Clin Exp Pediatr. 2022;65(4):182-187. Published online October 18, 2021

Web of Science 3 Crossref 5

· Thrombocytosis, common in newborns and infants (<2 years) (3%–13%), is caused by elevated thrombopoietin (TPO) concentrations.
· Serum TPO levels are significantly higher immediately to 1 month postnatal and decrease with age.
· Platelet counts are positively correlated with gestational age at birth and postnatal age.
· Thrombocytosis is more common in preterm than in term infants.
· Thrombocytosis in newborns is reactive and resolves spontaneously without complications.

DOI: https://doi.org/10.3345/cep.2021.00864

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