Clinical and Experimental Pediatrics

Original Article - Clinical trial

Effect of vitamin C supplement in treatment of childhood pneumonia requiring hospitalization: A randomized controlled trial

Chutima Phuaksaman, Katechan Jampachaisri, Klaita Srisingh

Background: The role of vitamin C in children with community-acquired pneumonia (CAP) in children is controversial; moreover, a standard dose is lacking.
Purpose: This study aimed to evaluate the ability of vitamin C to reduce symptom severity and length of hospital stay among children with CAP as well as determine its optimal dose. Methods: This randomized controlled clinical trial...

DOI: https://doi.org/10.3345/cep.2024.01970 [Accepted]

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Review Article

Nutrition

Macronutrients modified dietary intervention in the management of overweight/obese children and adolescents: a systematic review

Jihyun Park, Oh Yoen Kim

Clin Exp Pediatr. 2024;67(4):191-200. Published online July 11, 2023

· Dietary macronutrient modifications affect the body composition of and metabolic markers in children and adolescents.
· Hypocaloric diets, regardless of macronutrient composition, are reportedly effective for weight loss in obese children.
· Future interventional studies with meta-analyses that include Korean children and adolescents are needed to provide basic information applicable to this population.

DOI: https://doi.org/10.3345/cep.2023.00262

Gastroenterology

Clinical importance of immunonutrition in infants: a review of the recent literature

Ji Sook Park

Clin Exp Pediatr. 2022;65(7):337-343. Published online February 17, 2022

Web of Science 3 Crossref 4

Nutrients are important in the developing immune system. Human milk supplies diverse bioactives to prevent acute infection or chronic inflammation. Immunoglobulins, lactoferrin, and glutamine in human milk decrease gastrointestinal and respiratory infection. Human milk oligosaccharides promote the growth of intestinal microbiota, the gut barrier, and antimicrobial or antiviral activity. Micronutrients act as anti-inflammatory immunonutrients, too. However, the toxicity of some nutrients from an overdose should be considered.

DOI: https://doi.org/10.3345/cep.2021.00570

Nutrition

Components of human breast milk: from macronutrient to microbiome and microRNA

Su Yeong Kim, Dae Yong Yi

Clin Exp Pediatr. 2020;63(8):301-309. Published online March 23, 2020

Web of Science 173 Crossref 191

Human breast milk (HBM) is essential for the infant’s growth and development right after birth and is an irreplaceable source of nutrition for early human survival. Various infant formulas have many similarities to HBM in many components, but there is no perfect substitute for HBM. Recently, various breast milk components and their roles have been studied according to the development...

DOI: https://doi.org/10.3345/cep.2020.00059

Original Article

Clinical Experiences with Total Nutrient Admixture in 26 Cases

Yong Soon Kwon, Eun Jin Choi, Soon Ok Byun, Ji Sub Oh, Hwan Seon Ryu, Charles D. Sands

Clin Exp Pediatr. 1992;35(7):921-932. Published online July 15, 1992

Total Nutrient Admixture(TNA) is an intravenous nutrient system composed of dextrose, amino acid, fat, electrolytes, vitamins and trace elements in a single container which is administered over 24 hours. Twenty six seriously ill or premature neonatal patients reciving parenteral nutrition with TNA were studied by analyzing anthropometric parameters, laboratory values, and complications. The objective of the study was to test the...

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Cited By 28	Neurodevelopmental outcomes of preterm infants
Cited By 27	Long COVID in children and adolescents: prevalence, clinical manifestations, and management strategies
Cited By 23	Gut microbiota affects brain development and behavior
Cited By 23	Association of gut microbiota with obesity in children and adolescents
Cited By 21	Nonalcoholic fatty liver disease and insulin resistance in children

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