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Case Report

A case of mixed connective tissue disease presenting initially with Raynaud`s phenomenon

Soo Young Kim, Young Seok Choi, Young Ok Kim, Young Jong Woo

Clin Exp Pediatr. 2008;51(8):886-891. Published online August 15, 2008

Mixed connective tissue disease (MCTD) is characterized by diverse symptoms including rheumatoid arthritis, scleroderma, systemic lupus erythematosus, and dermatomyositis, associated with high titers of antibodies to extractable nuclear antigen (ENA), especially anti-ribonucleoprotein (anti-RNP) antibody. Since the first report of 25 cases with MCTD in adults, there have been only a few cases of MCTD reported in children. Here, we report...

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