Clinical and Experimental Pediatrics

Original Article

Pulmonology

Effect of vitamin C supplement in treatment of childhood pneumonia requiring hospitalization: a randomized controlled trial

Chutima Phuaksaman, Katechan Jampachaisri, Klaita Srisingh

Clin Exp Pediatr. 2025;68(9):690-699. Published online April 1, 2025

This study assessed the effects of vitamin C on children with community-acquired pneumonia (CAP). Vitamin C supplementation improved clinical symptoms within 48–72 hours compared to placebo but did not reduce the length of hospital stay (LOS). These findings suggest that vitamin C is beneficial for managing CAP severity, but does not affect LOS.

DOI: https://doi.org/10.3345/cep.2025.01970

A Clinical Analysis on Acute Lower Respiratory Tract Infections in Children Caused by Influenza Virus in Children

Kiehl Hyung Lee, Woo Kyung Kim, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Kyu Man Lee

Clin Exp Pediatr. 1998;41(12):1623-1631. Published online December 15, 1998

Purpose : Although annual epidemics occur, there are only a few clinical studies on influenza in Korea. We evaluated the epidemic and clinical features of acute lower respiratory tract infections in children by influenza virus. Methods : From Feb., 1995 to July, 1997, influenza virus isolations and clinical review were performed on hospitalized children with acute lower respiratory tract infections at...

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A Clinical Study on Acute Lower Respiratory Tract Infections by Adenovirus in Children

Ui Chong Chong, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Han Sung Kim, Kyu Man Lee

Clin Exp Pediatr. 1998;41(8):1070-1077. Published online August 15, 1998

Purpose : This study was performed to characterize the epidemiologic and clinical features of acute adenoviral lower respiratory tract infections. Methods : Culture and indirect immunofluorescence for adenovirus was done with nasopharyngeal aspirates from patients with acute lower respiratory tract infections from April to September, 1996. Cultured virus was serotyped for type 3, 4, and 7a by neutralization test, and medical...

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Diagnosis of Bordetella Pertussis Infections by Polymerase Chain Reaction

Mi Ran Kim, Hee Jung Kang, Hoan Jong Lee

Clin Exp Pediatr. 1996;39(9):1260-1270. Published online September 15, 1996

Purpose : Pertussis, a respiratory tract infection caused by Bordetella pertussis, is an important cause of morbidity in children. But diagnosis of pertussis is often delayed because of late development of typical symptoms and difficulties in culture. There has been no bacteriologically confirmed case of B. pertussis infection in Korea. Lower respiratoy tract may be involved in pertussis. We performed the polymerase chain reaction(PCR)...

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Clinical and Epidemiologic Features of Respiratory Syncytial Virus Infection

Hoan Jong Lee, Seong Hee Jang

Clin Exp Pediatr. 1992;35(10):1389-1401. Published online October 15, 1992

Although lower respiratory tract infection is a major cause of childhood morbidity in Korea and respiratory viruses are presumed to be important pathogens, there have been few studies available. We diagnosed RSV infection by virus isolation and immunofluorescence in children with lower respiratory tract infection, seen at Seoul National University Children's Hospital from Nov. 1990 to Jul. 1991. The results were...

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