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Case Report

Levamisole-Induced Reversible Agranulocytosis in Children with Steroid Dependent Nephrotic Syndrome

Su Jin Lee, Su Ja Hwan, Eun Seon Yoo, Seung Joo Lee

Clin Exp Pediatr. 1999;42(4):576-579. Published online April 15, 1999

Levamisole has been used for nephrotic syndrome due to its immunostimulating, immunomodulating, and steroid-sparing effects. Agranulocytosis, a serious side effect of levamisole, was rare and mostly associated with autoimmune disease, neoplastic disease and HLA B27 except one case in a nephrotic syndrome who was treated with high-dose(5mg/kg QOD) levamisole. This 15 year-old girl with steroid dependent nephrotic syndrome, who was...

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