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Original Article

The Growth Hormone Response to Growth Hormone-Releasing Hexapeptide (GHRP-6) in the Sprague Dawley Rat with Hypothyroidism

Sei Won Yang

Clin Exp Pediatr. 1994;37(1):89-98. Published online January 15, 1994

We studied the effects of growth hormone to subthreshold, threshold, or suprathershold dose of growth hormone-releasing hexapeptide (GHRP-6) in conscious and unconscious (anesthesized with ketamine and phenobarbital) female Sprague Dawley rats with hypothyroidism, induced with methimazole and compared these results with those in conscious and unconscious rats with euthyroidism. The results were as below; 1) In conscious rats, the peak GH response...

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