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Peripheral nerve sheath tumors in the head and neck in patients with APC gene deletion mutations: a case report and scoping review of the literature

Koral M. Blunt, Monirah Albathi, Miriam Conces, Tendy Chiang

Clin Exp Pediatr. 2025;68(6):428-433. Published online January 13, 2025

In this report, we describe our experience with a patient with an APC-related genetic syndrome who presented with a rare palatal lesion with characteristics of a schwannoma. We discuss the role of immunohistochemical staining in discerning the differential diagnosis.

DOI: https://doi.org/10.3345/cep.2024.01375

Case Report

Familial Adenomatous Polyposis Improved by COX-2 Inhibitor in a Child

Ki Won Oh, Se Young Kim, Hwan Suk Lee, Myung Hoon Lee, Byung Ho Choe

Clin Exp Pediatr. 2002;45(12):1591-1595. Published online December 15, 2002

Familial adenomatous polyposis(FAP) is an autosomal dominant disease characterized by numerous adenomas in the colorectum. Patients with FAP are always at risk of malignant transformation, so that colectomy is unavoidable. NSAID, such as sulindac, and selective COX-2 inhibitor, such as celecoxib, have shown a positive effect on FAP by causing polyp regression in some patients. We report a case of...

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