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Original Article

Correlation between Plasma Endothelin-1 Concentrations and Pulmonary Hypertension Associated with Congenital Heart Defects

Sang Ook Park, Su Eun Park, Hyang Jae Yoo, Young Tak Lim, Hee Ju Park

Clin Exp Pediatr. 1996;39(7):970-976. Published online July 15, 1996

Purpose : Endothelin-1 is the most potent vasoconstrictor. This study was investigated the correlation of plasma endothelin-1 and pulmonary hypertension associated with congenital heart defect. Methods : We evaluated the concentration of ET-1 in 24 cases of congenital heart disease diagnosed at the Department of Pediatrics, Pusan National University, from December 1993 to September 1994. The patients were divided into 2 groups according to mean...

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