Clinical and Experimental Pediatrics

Original Article

General Pediatrics

Bifidobacterium animalis subsp. lactis BLa80 for preventing allergic, respiratory, and gastrointestinal diseases in young children in China: a randomized double-blind placebo-controlled trial

Ke Chen, Xi Zhang, Kaihong Zeng, Jiayi Zhong, Shanshan Jin, Yang Nie, Ping Yang, Nianyang He, Haixia Chen, Yanmei Cao, Yunrong Fu, Ziji Fang, Wei Jiang, Changqi Lium

Clin Exp Pediatr. 2026;69(2):150-162. Published online October 30, 2025

Question: Can probiotic BLa80 bring long-term benefits to the health of young children?
Finding: This trial demonstrated that the daily administration of s BLa80 at 5×109 colony-forming units for 3 months in children can reduce the risk of eczema, upper respiratory tract infections, and acute tracheitis/bronchitis as well as beneficially improve the gut microbiome without any adverse effect.
Meaning: Bla80 can bring definite health benefits to young children.

DOI: https://doi.org/10.3345/cep.2025.01256

Case Report

A Case of Wiskott-Aldrich Syndrome

Dong Un Kim, Seung Hoon Han, Jin Han Kang, Joon Sung Lee

Clin Exp Pediatr. 1993;36(3):439-446. Published online March 15, 1993

Wiskott-Aldrich syndrome s an X-linked combined immunodeficency disorder characterzed by severely decreased number of platelets which are small in size, eczema resembling atopic dermatitis and recurrent infection. The serum of the patient contains elevated concentrations of IgA and IgE, whereas the IgG level is usually normal and IgM level is deecreased. The patient also shows skin test anergy and progressive...

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Original Article

The Effect of Infantile Eczema on the Development of Allergic Diseases.

Hee Sup Kim, Chang Sung Lee, Sung Hwan Kim, Sang Il Lee, Sung Jae Suh, Pyung Nam Kim

Clin Exp Pediatr. 1989;32(6):834-838. Published online June 30, 1989

For the evaluation of the correlation between infantile eczema and other allergic disorders in childhood, we performed the study which included questionnaire and allergic skin test, in July through August, 1987. Eight hundred and thirty three students were selected randomly from the middle class in Seoul. All the materials were grouped into four; early primary school group (6-8 years of age; EPSG), late primary...

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A Case of Eczema Herpeticum Occurring in Atopic Dermatitis.

Eun Young Choi, Min Sik Kim, Hey Sun Lee, Young Min Ahn

Clin Exp Pediatr. 1989;32(5):695-699. Published online May 31, 1989

We have experienced an 11-month-old male who had suffered from atopic dermatitis and subsequent eczema herpeticum which was confirmed by Tzank test and successfully treated with Acyclovlr. We report this case with a brief review of related literature.

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Cited By 30	Metabolic complications of obesity in children and adolescents
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