Journal of the Korean Pediatric Society 1989;32(6):834-838.
Published online June 30, 1989.
The Effect of Infantile Eczema on the Development of Allergic Diseases.
Hee Sup Kim1, Chang Sung Lee1, Sung Hwan Kim1, Sang Il Lee1, Sung Jae Suh2, Pyung Nam Kim2
1Department of Pediatrics, Paik Hospital Seoul, Inje University, Seoul, Korea
2School Health Center in Seoul , Seoul, Korea
소아습진이 알레르기질환 발생에 미치는 영향
김희섭1, 이창성1, 김성환1, 이상일1, 서성재2, 김평남2
1인제대학교 서울백병원 소아과학교실
2서울특별시립학교 건강관리소
Received: 7 October 1988   • Accepted: 1 December 1988
For the evaluation of the correlation between infantile eczema and other allergic disorders in childhood, we performed the study which included questionnaire and allergic skin test, in July through August, 1987. Eight hundred and thirty three students were selected randomly from the middle class in Seoul. All the materials were grouped into four; early primary school group (6-8 years of age; EPSG), late primary school group (9-11 years of age; LPSG), middle school group (12-14 years of age; MSG), and high school group (15-17 years of age; HSG). In general, the prevalence of infantile eczema was 26.1 % and that of asthma or wheezy bronchitis 10.8%. In case of skin prick test, when we included the materials which had larger reaction to any one of common respiratory allergens (house dust, house dust mite; D. pteronyssinus and D. farinae) in Korea than that to histamine, the positivity was 22-26% which was similar to prevalence of infantile eczema. Among the materials with infantile eczema, 21.6% has the clinical symptoms of bronchial asthma in EPSG which is significantly higher than 8.7% in non-eczema group (p < 0.005). But, in older age groups, the prevalence of asthma was similar in eczema and non-eczema group (p > 0.05). This suggests that skin hyperreactivity might have certain effects on the development of respiratory hyperreactivity in EPSG, and that functional development by age, for example immunologic development, may control the development of allergic disorders. on the other hand, skin test positivity did not have any significant difference between eczema and non-eczema of all age groups. This suggests that skin irritability might not affect the specific allergy skin test.
Key Words: AlIergic Development, Eczema, Asthma, Skin Test

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