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Original Article

Molecular analysis of childhood acute lekemia.

Hack Ki Kim, Kyong Su Lee, Sung Hoon Cho, Du Bong Lee

Clin Exp Pediatr. 1991;34(2):164-171. Published online February 28, 1991

Immunoglobulin (Ig) and T cell receptor 0 chain (TcR分) gene rearrangements can be used as ”genetic marker” of lineage and clonality in the study of lymphoproliferative disease. We analyzed genomic DNA of the bone marrow mononuclear cells from twenty six patients with acute leukemia in children. The patients were seventeen cases of acute lymphocytic leukmia (ALL), seven cases of acute nonlymphocytic leukemia (ANL) and...

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