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Review Article

Nephrology (Genitourinary)

Atypical hemolytic uremic syndrome and eculizumab therapy in children

Seong Heon Kim, Hye Young Kim, Su Young Kim

Clin Exp Pediatr. 2018;61(2):37-42. Published online February 28, 2018

Crossref 5

Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing Escherichia coli-associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has been studied recently. aHUS is a rare, chronic, and devastating disorder that progressively damages systemic organs, resulting in stroke, end-stage renal disease, and death. The traditional treatment for aHUS is...

DOI: https://doi.org/10.3345/kjp.2018.61.2.37

Case Report

Atypical Hemolytic Uremic Syndrome Associated with Streptococcus pneumoniae Infection

Hyun Sug Lee, Ja Wook Koo, Sang Woo Kim, Hyun Soon Lee

Clin Exp Pediatr. 2004;47(2):217-222. Published online February 15, 2004

Hemolytic uremic syndrome is the most common cause of acute renal failure in childhood. Atypical hemolytic uremic syndrome which is not usually associated with prodromal symptoms has a higher mortality rate and more tendency to progress to chronic renal failure. Children younger than two years of age are a more susceptible to pneumococcal infection and can develop more serious disease....

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