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Original Article
A case of benign recurrent intrahepatic cholestasis.
Jae Hong Park, Sung Sub Sim, Soo Young Kim, Hee Joo Jeon, Chan Yung Kim
Clin Exp Pediatr. 1991;34(12):1745-1752.   Published online December 31, 1991
The clinical picture of beingn recurrent intrahepatic cholestasis (BRIC) consists of multiple epi- sodes of cholestatic jaundice without extrahepatic bile duct obstruction. Since first description by Summerskill and Walshe in 1959, almost 100 patients with BRIC have been described. The mechanism involved in the initiation and perpetution of an episode of cholestasis are unknown. Altered bile acid metabolism has been proposed to play a...


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