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Background: Childhood-onset lupus nephritis (cLN)
is an aggressive disease. Although histological class has
historically guided its treatment, its prognostic value
remains limited. Although the National Institutes of
Health (NIH)-modified activity index (AI) and chronicity
index (CI) incorporate glomerular and tubulointerstitial
changes and may provide better prognostic insight, their
utility in cLN is not well established.
Purpose: Here we aimed to assess the utility of the
NIH-modified-modified AI and CI... |