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Original Article

Polymorphisms of interleukin-1β promoter in simple febrile seizures

Jang Won Yoon, Eun Jung Choen, Young Hyuk Lee

Clin Exp Pediatr. 2008;51(9):1007-1011. Published online September 15, 2008

Purpose : Febrile seizure (FS) is the most common type of seizure. The role of genetic factors in FSs has long been recognized. A positive family history can be elicited in 25-40% of patients with FSs; nonetheless, the genes responsible for FSs in the majority of the population remain unknown. Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that acts as an...

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