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Original Article

Association of HLA-G gene promoter haplotype with childhood IgA nephropathy in the Korean population

Hwan Hee Jung, Won Ho Hahn, Byoung Soo Cho, Sung Do Kim

Clin Exp Pediatr. 2010;53(4):548-553. Published online April 15, 2010

Purpose : IgA nephropathy (IgAN) is the most commonly occurring form of chronic glomerulonephritis in pediatric cases.Human leukocyte antigen (HLA) genes have been implicated in various inflammatory and autoimmune diseases. The present study was conducted to investigate the association between 2 single nucleotide polymorphisms (SNPs) of the HLA-G gene and childhood IgAN. Methods : The authors analyzed and compared HLA-G gene...

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