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Original Article

Decrease of Plasma Th2 Cytokines by Interferon(IFN) -γ Therapy in Atopic Dermatitis

Geun Woong Noh, Woo Gill Lee, Dong Hee Cho, Ki Young Lee

Clin Exp Pediatr. 1998;41(8):1128-1134. Published online August 15, 1998

Purpose : Atopic dermatitis is characterized by reduced IFN-γ production and increased IL-4 production. As a result, IgE production increases in atopic dermatitis. In the previous studies, it was reported that recombinant IFN-γ therapy is effective in treatment of severe atopic dermatitis. In this study, changes of plasma IFN-γ, IL-4, IL-5 and IL-10 concentration by IFN-γ therapy were studied in...

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