Clinical and Experimental Pediatrics

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Original Article

M J Na, E W Park, W H Choi, K W Kim, D W Kim

Clin Exp Pediatr. 1990;33(5):721-726. Published online May 31, 1990

Epidermolytic hyperkeratosis is a type of ichthyosis. We present a case of epidermolytic hyperker- atosis in 7 months old male infant who developed generalized erythematous hyperkeratosis & vesicles at birth. Later, the skin lesions progressed to characteristic thick, grayish dark brown scales affecting flexural & intertriginous areas. Histological examination revealed hyperkeratosis, vacuolation of Malpighian cells & markedly thickening of granular layer containing many keratohyaline granules.

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