Clinical and Experimental Pediatrics

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Original Article

LIN28B polymorphisms are associated with central precocious puberty and early puberty in girls

Sung Won Park, Seung-Tae Lee, Young Bae Sohn, Sung Yoon Cho, Se-Hwa Kim, Su Jin Kim, Chi Hwa Kim, Ah-Ra Ko, Kyung-Hoon Paik, Jong-Won Kim, Dong-Kyu Jin

Clin Exp Pediatr. 2012;55(10):388-392. Published online October 29, 2012

Crossref 25

Purpose

Single-nucleotide polymorphism (SNP) markers within LIN28B have been reported to be related to the timing of pubertal growth. However, no study has investigated the frequency of genetic markers in girls with precocious puberty (PP) or early puberty (EP). This study aimed to determine the frequency of putative genetic markers in girls with PP or EP.

Methods

Genomic DNAs were obtained from 77...

DOI: https://doi.org/10.3345/kjp.2012.55.10.388

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