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Treatment of Aplastic Anemia
Nak Gyun Chung, Kyu Jin Bhang, Woo Gun Choi, Hack Ki Kim, Kyong Su Lee, Man Kyu Yang
Clin Exp Pediatr. 1993;36(8):1059-1066.   Published online August 15, 1993
We performed this study to evaluate the therapeutic responses of bone marrow transplantation and immunosuppressive therapy for aplastic anemia in 103 cases(68 severe and 35 moderate). Among them, 15 cases with severe aplastic anemia having HLA-identical sibling donor underwent bone marrow transplantation, and cases (53 severe and 35 moderate cases) without available HLA-identical sibling donor had received immunosuppressive therapy using...
Assessment by Question-Naire of Disease Status of the Pupils in Two Primary Schools in Seoul
Jae Kyung Choi, Nam Soo Kim, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1993;36(7):994-1001.   Published online July 15, 1993
We studied the disease status by question-naire in Seoul of the pupils in two primary schools on May, 1991 and carried out statistical analysis of their results. The following results were observed: 1) Total number of answered pupil was 2330;1103 were male and 1227 were female and the ratio of male to female was 1:1.1. Average age was 9.27 years. 2) Number of...
Atypical Presentation of Acute Glomerulonephritis
Hyun Ho Shin, Thy Hyung Park, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn, Young Tae Ko, Moon Ho Yang
Clin Exp Pediatr. 1993;36(7):987-993.   Published online July 15, 1993
Form March 1982 to December 1991, 110 cases of typical post-streptococcal glomerulonephritis and 25 cases of Atypical acute glomerulonephritis were clinically investigated at Department of pediatrics, Kyung Hee University Hospital, and follwing Data were obtained. 1) Male to Femal ratio was 1.8:1 (Atypical AGN). Peak incidence was from 7 to 12 years. 2) The most common preceding infections were upper respiratory infection,...
Plasma Norepinephrine Levels in Infants and Children with Congestive Heart Failure
Sang Woog Lee, Myung Sung Kim, Sang Lak Lee, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1993;36(7):982-986.   Published online July 15, 1993
To characterize the sympathetic nervous system response to congestive heart failure in infants and children, plasma norepinephrine levels were measured in 29 patients aged 4 months to 15 years undergoing routine cardiac catheterization at Dong San Hospital, Keimyung University during the period of 4 months from November 1990 to February 1991. Plasma norepinephrine levels were significantly higher in patients with heart...
A Clinical Study on Patients with Porencephaly
Sung Yoon Cho, Jai Yoon Kim, Kwang Sun Han, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1993;36(7):975-981.   Published online July 15, 1993
Porencephaly is relatively rare condition defined by a defect or cavity in the cerebrum owing to a developmental malformation or to a destructive lesion. Forty-five porencephaly patients diagnosed by Brain CT were clinically analyzed and the following results were obtained. 1) By the age group presenting initial symptoms, the peak incidence was from 1 month to below 3 years old. 2) In initial...
The Impact of Large Amount Whole Cow's Milk Intake on Iron Status in Early Childhood
Sung Yoon Byun, Mi Ran Park, In Sang Jeon
Clin Exp Pediatr. 1993;36(7):968-974.   Published online July 15, 1993
To determine the impact of intake large amount whole cow's milk (WCM) on iron status during early childhood(18~36 months), selected indices of complete blood count (CBC) and iron status were compared between the WCM large amount intake group (n=20) and small amount intake group (n=20). WCM large amount intake children's mean hemoglobin and mean hematocrit were 9.6¡¾1.7g/dl and 30.8¡¾4.5% respectively. These...
Clinical Consideration between the Type of pneumonia and cold Agglutinin Titer, and Mycoplasma Antibody Titer caused by Mycoplasma pneumonia in Children
Byung Yeon Kim, Hyang Suk Lee, Ill Kyung Kim, Chang Hee Choi, Jyung Ho You
Clin Exp Pediatr. 1993;36(7):959-967.   Published online July 15, 1993
The authors analysed 261 cases of mycoplasmal pneumonia in chidren who were admitted to the pediatric department of Seoul Adventist Hospital between July 1986 and June 1991. The result obtained were as follows; 1) Yearly distribution of the cases showed high in 1987 and 1991, but no significant difference was noted in seasonally or monthly distribution. 2) The peak incidence of age was...
Clinical Study of Intussusception in Infancy and Childhood -Comparing the Result of Barium Enema with that of Air Enema-
G.H. Lee, N.M. Park, S.C. Kim, M.J. Chey, S.J. Shon, K.H. Kim, H.S. Lee, Y.S. Lee
Clin Exp Pediatr. 1993;36(7):951-958.   Published online July 15, 1993
Intussusception is the most common cause of acquired intestinal obstruction during infancy and early childhood and requires early diagnosis and treatment. We observed 431 cases of intussusception who admitted at Chungang Gil Hospital from January 1987 to June 1991, and compared the result of treatment with Barium Enema in 302 cases with that of Air Enema in 129 cases. The results were...
A Clinical Review of Congenital Gastrointestinal Anomalies
Dong Hak Shin, Woo Hyun Park, Chul Young Bae
Clin Exp Pediatr. 1993;36(7):944-950.   Published online July 15, 1993
A clinical review was done on 343 infants and children diagnosed and operated at the Department of Pediatric Surgery in Keimyung University, Dong San Medical Center for congenital gastrointestinal anomalies from January, 1988 to December, 1991. The results are summarized as follows; 1) The most prevalent age group of congenital gastrointestinal anomaly was within first week after birth, and infants within 3months...
Plasma Levels of Oral Methotrexate in Children Receiving Maintenance Chemotherapy for Acute Lymphocytic Leukemia
Soo Kwan Lee, Kih Yeon Song, Young Hee Hwang, Young Hwan Lee, Jeong Ok Hah, Chun Dong Kim
Clin Exp Pediatr. 1993;36(7):936-943.   Published online July 15, 1993
This study was conducted to investigate plasma levels of oral methotrexate in rabbits and children receiving maintenance chemotherapy for acute lymphocytic leukemia. Eight New Zealand white rabbits, weighing 2kg in body weight, were divided into 3 groups and 5mg of methotrexate from 3 different manufactorying company was administered to the each group rabbits via nasogastric tube. Time to peak concentration ranged from...
Clinical Observation for Low Birth Weight Infants
Hye Jin Lee, Soon Wan Kwon, Soon Ok Byun, Ji Sub Oh
Clin Exp Pediatr. 1993;36(7):928-935.   Published online July 15, 1993
Clinical observations were made on 338 low birth weight infants, who were delivered at Pusan Wallace Memorial Baptist Hospital, during the 3 year periods from 1989 to 1991. The results were as follows; 1) The incidence of LBWI was 5.6% and sex ratio was 1:1.09. Among them AGA was 62.7%. 2) Of all infants, 47.3% were in the birth weight range of 2251-2500...
The Changes of Fetal Hemoglobin in Preterm and Small for Gestational Age Newborn Infants
Eun Ae Park, Gyoung Hee Kim
Clin Exp Pediatr. 1993;36(7):919-927.   Published online July 15, 1993
The fetal hemoglobin, which is structurally different from adult hemoglobin, has higher affinity for oxygen and higher resistance to denaturation with alkali than adult hemoglobin. Intrauterine growth retarded neonates have highter mortality and morbidity than normal neonates. In this article, to determine the changes of fetal hemoglobin by gestational age in infants appropriate in wieght for gestational age (AGA) and to...
Comparison and diagnostic Accuracy of Stable Microbubble Rating Test and Shake Test for the Early Detection of Respiratory Distress Syndrome
Hyeon Gon Kim, Sang Hyun Byun, Young Hun Chung
Clin Exp Pediatr. 1993;36(7):913-918.   Published online July 15, 1993
Respiratory distress syndrome of preterm infants remains a significant cause of morbidity and mortality. Early, just after birth, prediction and recognition of RDS is so important. The precision and reliability of the stable microbuble test (SMR) and shake test as a predictor of respiratory distress syndrome were studied. A 11-=neonate who was born at Chungnam National University Hospital between November 1991...
Studies on the Prognostic Marker in Minimal Change Nephrotic Syndrome
Byoung-Soo Cho
Clin Exp Pediatr. 1993;36(7):906-912.   Published online July 15, 1993
Childhood minimal change nephrotic syndrome (MCNS) is often associated with hyper-sensitivity reactions and considered to be caused by immune dysfunction. The elevated serum IgE levels and atopic symptoms have been frequently associated in these patients. The present therapy for MCNS mainly depends on corticosteroids, alkylating agents such as chlorambucil, cyclophosphamide and cyclosporin A (Cy-A). Howerver, frequent relapses and severe side effects...
A Clinical Study on Febrile Convulsion
Jung Hwan Lee, Ki Hwan Yoo, Yong Sook Hong, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 1993;36(6):850-857.   Published online June 15, 1993
Although febrile convulsion(FC) is a common clinical entity with a high recurrence rate, no specific factors have been identified to be highly predictive of its recurrence. A total to 114 cases of FC identified during a 28 month period (January, 1989-May, 1991) was analysed. A silght predominance of boys over girls(1.3 to 1.0) was observed. The majority of cases(89.4%) were under 3...
Hand, Foot and Mouth Disease Associated with the Aseptic Meningitis in Seoul, 1990
Young Ah Lee, Sei Ho Oh, Soo Jong Hong, Young Hwue Kim, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1993;36(6):842-849.   Published online June 15, 1993
We performed clinical and virological studies on 79 children with hand, foot and mouth disease(HFMD) who had been admitted or visited to the department of Pediatrics, Asan Medical Center from February to August, 1990. The results were as follows; 1) There were total of 79 cases with hand, foot and mouth disease during this period. The aseptic meningitis was combined in 18cases(22.8%) 2)...
The Gastrofiberscopic Findings in Pediatric Patients
Yong Min Chung, Hwa Ja Kim, Hann Tchah, Sang Kyu Park, Ho Jin Park
Clin Exp Pediatr. 1993;36(6):837-841.   Published online June 15, 1993
We observed 240 cases ranging in age from 3 months to 15 years seen by gastrofiberoscopy in the department of pediatrics of Seoul Red Cross Hospital from March 1990 to October 1992 and following results were obtained. 1) The male to female ratios in total cases and 89 patients complaining of abdominal pain for more than one month were 0.94:1 and...
Serum Alkaline Phosphatase Activity after Intravenous Administration of Albumin Preparation
June Huh, Kang Mo Ahn, Ja Wook Koo, Il Soo Ha, Hae Il Cheong, Yong Choi
Clin Exp Pediatr. 1993;36(6):830-836.   Published online June 15, 1993
Serum alkaline phosphatase(AP) activity is elevated in hepatobiliary disease, bone disease, pregnancy and certain neoplasms. Recently we experienced marked elevation of serum AP activity after administration of ablumin preparation in nephrotic patients who suffered from hypovolemic symptoms. So serum AP activity and the isoenzymes in the albumin preparations & patient뭩 serum after the administration of albumin preparation were studied. Serum...
Effect of Different Levels of the Dietary Protein on Long Term Prognosis of Experimental Renal Damage
Choon Haeng Lee, Sang Joo Han, Hong Jin Lee, Won Il Park, Kyung Ja Lee, Young Eui Park, Min Chul Lee, Tae Heon Yoon
Clin Exp Pediatr. 1993;36(6):820-829.   Published online June 15, 1993
We examined the effect of various levels of dietary protein on long term prognosis of Adriamycinephropathy of S-D rat, fed with high protein(30%), intermediately low(10%), and strictly low(5%) protein diet for 15 weeks 1) In rats fed with strictly low protein diets(5%), proteinuria and serum creatinine decreased and creatinine clearance and histological changes were relatively well preserved. But hypoproteinmia and weight...
Serum Eosinophil Cationic Protien(ECP) in Children with Atopic Astham
Dae Cheol Kim, Ha Baik Lee
Clin Exp Pediatr. 1993;36(6):810-819.   Published online June 15, 1993
Eosinophils play a major role in the airway inflammation in asthma. To werify an association between airway responsiveness of asthmatics and eosinophil and/or ECP, we measured serum ECP in 23 children with atopic asthma during acute attacks and stable, and in 10 normal healthy controls. Peak flows were monitored in 15 children. The data suggest that serum ECP levels were higher...
Clinical Observation of Aseptic Meningitis Associated with Mucocutaneous Lymph Node Syndrome
Jae Hee Han, Seon Jin Ji, Mee Kyung Namgoong, Hae Yong Lee, Jae Seung Yang, Baek Keun Lim
Clin Exp Pediatr. 1993;36(6):805-809.   Published online June 15, 1993
Clinical observation was carried out for 147 patients with mucocutaneous lymph node syndrome(MCLS) who were admitted to the Department of Pediatrics, Wonju Cristian Hospital during the period from June, 1983 to June, 1992. A spinal tap was performed on 114 of these patients and the following results were obtained. 1) The incidence of aspetic meningitis in patients with MCLS was 52.6%.(60...
Outcome in Infants of Mothers with Systemic Lupus Erythematosus
Chang Ryul Kim, Young Pyo Chang, Hee Seop Kim, Mi Jung Kim, Byung Il Kim, Jung-Hwan Choi, Chong Ku Yun, Bo Hyun Yoon, Hee Chul Syn, Syng Wook Kim, Seon Yang Park, Hahng Lee
Clin Exp Pediatr. 1993;36(6):791-804.   Published online June 15, 1993
A large proportion of patients with systemic lupus erythematosus(SLE) are women of reproductive age. Their fetal outcome is undoubtedly less favourable than in haelthy women. Although there is no evidence of an increase in congenital anomalies, increased frequencies of miscarriage, stillbirth, growth retardation, and preterm delivery are recognized It mainly depends on the compromise of uteroplacental circulation such as renal...
Clinical Assessment of Neonatal Transient Tricuspid Insuffieciency - Doppler Echocardiographic Study-
Se Geun Park, Dong Gun Park, Ji Hee Park, Chang Sung Son, Joo Won Lee, Young Chang Tockgo
Clin Exp Pediatr. 1993;36(6):785-790.   Published online June 15, 1993
Eight neonates with transient tricuspid insufficiency are presented which was confirmed clinical and two dimensional echocardiographic assessment. We found that two dimensional Doppler echocardiography was very useful in the detection of transient tricuspid insufficiency during neonatal age as noninvasive method. Transient tricuspid insufficiency is a clinical disorder in the newborn period caused by myocardial dysfunction, secondary to asphyxia with or without...
Clinical Observation on Prematurity Subjected for EEG
Chul Soon Park, Soon Wha Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1993;36(6):778-784.   Published online June 15, 1993
This study included fifty two premature babies in whom EEG was performed at National Medical Center, from Jan. 1990 to Jun. 1991. Clinical and EEG recirdes of akll subjects were analyzed and the following results were obtained . 1) The day of first EEG performed were; 11 cases within 10 days, 20 cases from 11 days to 20days, 13 cases from21...
A Clinical Study of Neonatal Sepsis
Hyoung Shim Chang, Jung Sook Park, Young Ho Lee, Ahn Hong Choi
Clin Exp Pediatr. 1993;36(6):771-777.   Published online June 15, 1993
The 35 newborns with neonatal sepsis admitted to the Neonatal Intensive Care Unit of Dong-A Univesity Hospital during 2 years and 6months from April 1990 to October 1992, and were reivewed on the bases of incidence, clinical manifestations, underlying conditions, etiologic organisms, results of antibiotics sensitivity test and mortality rate. The result were summarized as follows; 1) The incidence of neonatal sepsis...
Bilateral Torsion of the Testes in a Newborn Infant
Eun Sook Kim, Hang Mi Kim, Song Kwang Jung
Clin Exp Pediatr. 1993;36(5):721-724.   Published online May 15, 1993
We report one case of bilateral testicular torsion. A 4000 gm male infant, born by cesarean section due to induction failure at 42 weeks gestation, was hospitalized at 9 days of age secondary to bilateral testicular mass. Physical examination revealed an healthy baby with enlarged, firm, nontender mass on both sides of the scrotum. Transillumination of the mass shwed no transmission...
Growth Outcome in Congenital Hypothyroidism
Mi Jung Park, Ho Seong Kim, Duk Hi Kim
Clin Exp Pediatr. 1993;36(5):713-720.   Published online May 15, 1993
Congenital hypothyroidism is one of the most common endocrine disease in childhood and it causes not only mental retardation but also growth retardation. There were many papers about evaluation of developmental outcome in congenital hypothyroidism, The aim of this study was to evaluate growth outcome in congenital hypothyroidism. We evaluated 65 patients with congenital hypothyroidism diagnosed at yonsei University College...
Blood Pressure Measurement of School-Aged Children in Goesan
Seong Hoon Hah
Clin Exp Pediatr. 1993;36(5):705-713.   Published online May 15, 1993
Since clinical significance of blood pressure level in childhood has been known, a several studies for the purpose of establishing normal blood pressure referce values in Korean school-aged children were performed. The author of this article measured normal blood pressure values for children in an elementary school, and two middle schools of Korean rural area using mercury sphygmomanometer. The results...
Periventricular Leukomalacia -Ultrasonographic Findings, Risk Factors and Neurological Outcome-
Kyeong Hee Cho, Myoung Jae Chey, Sejung Sohn, Kil Hyun Kim, Hak Soo Lee, Young Seok Lee, Dae Joong Kim
Clin Exp Pediatr. 1993;36(5):693-704.   Published online May 15, 1993
The thirty eight newborn infants with periventricular leukomalacia who were admitted to the neonatal intensive care unit of Gil General Hospital from March 1, 1988 to June 30, 1991, were investigated for ultrasonographic findings, risk factors and neurological outcome. The results were as follows: 1) There were 38 cases of PVL including 21 echogenic flarings and 17 cystic PVL뭩. 2) Mean birth weight...
A Prospective Study of Totally Implanted Venous Access System in 19 Children with Cancer
Kyung Duk Park, Eun Sil Dong, Seong Hoon Ha, Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn, Seong Eun Jun, Gui Won Park
Clin Exp Pediatr. 1993;36(5):687-692.   Published online May 15, 1993
A totally implanted venous access system was inserted in 19 children with cancer. The devices were utilized for the administration of antineoplastic drug, parenteral fluids, antibiotics, and blood products. Total duration of implantation was 4,046 days for 23 implanted system (range 7-445 days). Complications included cather infection (0.247/100 catheter day), occlusion (0.692/100 catheter days), and dislodgement of needle (0.643/100 catheter...
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