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A Clinical Study on Childhood Leukemia
Joo Huh, Jong Bum Shin, Soon Yong Lee
Clin Exp Pediatr. 1994;37(5):655-665.   Published online May 15, 1994
Clinical analysis of 170 patients with childhood leukemia was made, who were admitted to the department o Pediatrics, Pusan Paik Hospital, Inje University, College of Medicine during 10 years from 1981 to 1990. The results were as follows: 1) The annual number of the patients with childhood leukemia was in the range of 6~25 cases. And the annual rate of the...
Clinical Approach of Ultrasonography in the Diagnosis of Intussusception in Infant and Children
Hee Tag Lim, Jin Kil Park, Hong Ju Choi, Jae Sam Kim, Hyo Kyung Shin, Chul Hoi Gu
Clin Exp Pediatr. 1994;37(5):649-654.   Published online May 15, 1994
Thirty consecutive partient seen in a pediatric out patient and emergency department, in whom the diagnosis of intussusception was considered, had an ultrasound examination of the abdomen before the barium enema. The peak age was 5~12 month(range 4~34 month). Intussusception was detected by ultrasonography in all 25 cases proved by barium enema(sensitivity 100%). Normal findings on ultrasonography correlated with negative barium...
Periventricular-Intraventricular Hemorrhage in the Full-term Infant
Hee Sup Kim, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun, In One Kim
Clin Exp Pediatr. 1994;37(5):642-648.   Published online May 15, 1994
Intraventricular hemorrhage (IVH) is common in the premature infants and occurs mainly in subependymal germinal matrix. In contrast, IVH in the term infants is rare and different in pathogenesis and bleeding sites from those of the premature infants. Most studies of IVH in term infants have been studied by computerized tomography and postmortem examination. Brain ultrasonography which has become a...
A Clinical Study of retinopathy of Prematurity
Jong Won Lee, Jin Kyung Jung, Ji Hae Kang, Ghee Young Jung, Moo Ung Kim
Clin Exp Pediatr. 1994;37(5):636-641.   Published online May 15, 1994
Among 666 premature infants or low birthweight infants who were admitted in NICU of st. Francisco General Hospital from January 1990 to Jun 1992, 96 infants were diagnosed as retinopathy of prematurity by indirect ophthalmoscope. The result were follows: 1) Among 666 patients, retinopathy of prematurity developed in 96 patients(14.1%) 2) The high incidence was observed in low birthweight and small gestational age. 3)...
Clinical Study on Very Low Birth Weight Infants
Sha Young Choi, Dae Young Jang, Oh Kyung Lee, Wan Seob Kim
Clin Exp Pediatr. 1994;37(5):628-635.   Published online May 15, 1994
Medical records of very low birth weight infants weighing less than 1500 grams at birth were reviewed and analyzed. One hundred and forty three infants who were admitted to neonatal intensive care unit of Presbyterian Medical Center, including those who were born and transferred from other hospitals, from January 1987 to December 1991 were examined and the following results were obtained; 1)...
Diagnostic value and Relationship of the between Stable Microbubble rating Test and Shake Test for the Prediction of Neonatal Respiratory distress Syndrome
Seong Jin Ha, Dong Kyun Ryu, Oh Kyung Lee, Wan Seob Kim
Clin Exp Pediatr. 1994;37(5):620-627.   Published online May 15, 1994
Respiratory distress syndrome (RDS) in the newborn infants remains a major cause of mortality and morbidity in the newborn period despite much improvements in neonatal intensive care and artificial ventilatory techniques. Gastric fluid was obtained from 151 patients within 6 hours after delivery. The sensitivity, specificity, and predictive value of the simple shake test (133 cases) and stable microbubble rating...
Morphological Classification of Left Superior Vena Cava and Analysis of Associated Cardiac Anomalies
Eun Joo Choi, Jong Kyun Lee, Seok Min Choi, Jun Hee Sul, Sung Kyu Lee
Clin Exp Pediatr. 1994;37(5):612-619.   Published online May 15, 1994
The persistend left superior vena cava(LSVC) is not rare cardiovascular developmental anomaly occurring both in association with congenital heart disdease and as an isolated anomaly of no hemodynamic importance. We have studied 73 cases of the LSCV out of 1,060 cases of congenital heart disease catheterized at Yonsei Cardiovascular Center. We conducted the study with a view point of position of...
Normal Fetal echocardiography
Seock Joong Yoon, Sung Jin Hong, Hyung Gu Cho, Jung Wan Yoo, Dong Chul Park
Clin Exp Pediatr. 1994;37(5):606-611.   Published online May 15, 1994
Fetal echocardiography is used by means of decleration of fetal cardiac anaxtomy, to estabilish the diagnosis of congenital heart disease in utero. We attemped fetal echocardiography to ninty three pregnant women after intra uterine period 24 weeks, and estimated cardiac circumference, cardiac axis, pulmonary atery root diameter, arortic root diameter, diameter of inferior vena cava, diameterof superior vena cava, and...
Evaluation of Pulmonary Venous, Mitral and Aortic Flow Pattern by Doppler Echocardiography in Neonates
Hye Soon Kim, Young Mi Hong, Gyoung Hee Kim
Clin Exp Pediatr. 1994;37(5):596-605.   Published online May 15, 1994
Pulmonary vein velocities have recently been estimated in conjunction with mitral flow velocities to increase our understanding of ventricular filling. The advent of transesophageal echocardiography with pulsed doppler imaging capability has provided a method by which both the mitral valve and pulmonary vein velocities can be easily recorded because of the posterior approach providing unimpeded interrogation of cardiac structures. The purpose...
A Clinical Study on Twins
Kwang Sin Kim, In Ah Cha, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(4):537-546.   Published online April 15, 1994
We observed 233 twins and 2 triplets cases among 16,774 newborns delivered at Kwangju Christian Hospital during 5 years from Jan. 1986 to Dec. 1990. The results obtained are as follows : 1) The overall incidence of twin pregnancy was 1 : 72 (1.4%) and that of triplets 1 : z8387 (0.01%). 2) The average male-female sex ratio of twins was 1.06 :...
Effect of High Frequency Ventilation on Tension Pneumothorx Induced by Conventional Ventilator
Jae Han Kim, Jung Mi Lee, Sang Heuck Ma, Jae Uk Lee, Sang Geel Lee
Clin Exp Pediatr. 1994;37(4):527-536.   Published online April 15, 1994
Four cases of newborn with tension pneumothorax induced by a conventional ventilator were admitted to our nursery January 1. 1992 to June 30. 1992 and they were managed by high frequency ventilator (Infrasonic Infant Star Venilator). In contrast, four cases of newborn with tension pneumothorax who were continuously on the conventional ventilator, were included as a control group. They were...
Primary Cutaneous Aspergillosis in Leukemic Children
Jin Young Park, Mee Ran Kim, Hee Young Shin, Hoan Jong Lee, Hyo Seop Ahn, Je Guen Chi
Clin Exp Pediatr. 1994;37(4):520-526.   Published online April 15, 1994
Primary cutaneous aspergillosis is rare. In this report we describe primary skin infection by Aspergillus in 9 children with leukemia. The skin lesion was characterized clinically by erythematous macule and papule associated with pain and itching, followed by a rapid progression to ulcer and central black eschars with raised erythematous border at the site of venipuncture, insertion of intravenous cannula,...
A Clinical Observation in 14 Children with SLE
Jin Nyoung Park, Jai Kyoung Choi, Ha Baik Lee, Hahng Lee
Clin Exp Pediatr. 1994;37(4):510-519.   Published online April 15, 1994
To elucidate the clinical characteristics of childhood onset systemic lupus erythematosus (SLE), we carried out a retrospective reivew on medical records of fourteen patients who were diagnosed as SLE on the base of 뱓he 1982 revised criteria for the SLE?(by american Rheumatism Association) at the Department of pediatrics, Hanyang University Hospital from January 1980 through August 1992. The results were summerized...
Echocardiographic Evaluation of the Changes of the Interventricular Septal Morphology in Postoperative Tetralogy of Fallot Patients
Im Jae Park, Jun Hee Sul, Jong-Kyun Lee, Seok Min Choi, Jo Won Chung, Sung Kyu Lee, Bum Koo Cho
Clin Exp Pediatr. 1994;37(4):502-509.   Published online April 15, 1994
The hemodynamic feature of the tetralogy of Fallot (TOF) is best characterized by equality of left and right ventricular peak systolic pressure. The interventricular septum is flattened and thickened. Even after the right ventricular pressure is normalized in the postoperative period, the morphological abnormality continues for some time. We have analyzed the morphological changes of the IVS echocardiographically after total...
Ultrasonographic Diagnosis of Congenital Hypertrophic Pyloric Stenosis
Chung Hyun Yun, Kwang Sin Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(4):494-501.   Published online April 15, 1994
Ultrasonic evaluation of the pylorus was performed in a group of 22 infants clinically suspected of having Congenital Hypertrophic Pyloric Stenosis (CHPS), from march 1990 to July 1991. In every case the diagnosis of CHPS was confirmed by surgery. Ten normal babies served as the control group. 1) In CHPS group, the mean age on admission was 36.7¡¾16.4 days, and male...
Plasma Atrial Natriuretic Peptide Concentrations of the Pulmonary artery, Aorta and Veins in Children with Cardiac Disease
Kang Il Lee, Nam Geun Heo, Myung Chul Hyun, Sang Bum Lee, Eun Kyoung Yang, Won Jung Lee
Clin Exp Pediatr. 1994;37(4):481-493.   Published online April 15, 1994
To study the site of release and factors affecting the releases of the atrial natriuretic peptide (ANP) in the pediatric patients, we measured the plasma ANP concentrations in 23 normal healthy children, 19 patients with congestive heart failure and 16 patients with cardiac disease undergoing diagnostic cardiac catheterization. The following results were obtained. 1) The plasma ANP concentrations of the vein (226.3¡¾74.9...
Clinical Studies on Congenital Heart Diseases
Kyeong-Ah Lee, Tae-Guen Song, Hyun-Kee Chung
Clin Exp Pediatr. 1994;37(4):472-480.   Published online April 15, 1994
The clinical studies were performed on 304 patients with heart disease who had been received corrective heart surgery at Kosin Medical Center from July, 1984 to December, 1991. The results were follows : 1) Out of 304 patients, 162 cases (53.3%) were male and 142 cases (46.7%) were female and sex ratio was 1.15 : 1.35 cases (11.5%) had clinical cyanosis and...
A Study on Non-Organic Failure to Thrive Infants
Keun Lee
Clin Exp Pediatr. 1994;37(4):464-471.   Published online April 15, 1994
Failure to thrive(FTT) is defined when the weight of a child is below 3rd percentile or when there is sudden weight loss in history. If organic cause of the weight loss is not found, it is called non-organic failure to thrive (NETT). Relatively little attention has been paid to NFTT in Korea for various reasons and the incidence is...
Mechanism of Impaired Growth Hormone Response in Children with Simple Obesity
Moon Sung Park, Mi Jung Park, Ho Seong Kim, Duk Hi Kim
Clin Exp Pediatr. 1994;37(4):457-463.   Published online April 15, 1994
Obesity is associated with an impairment of the hormone secretion elicited by all stimuli known to date, but the basic mechanism of this alteration is unknown, To determine whether obesity is associated with a chronic state of tonic somatostatin, several tests with growth hormone stimuli such as GHRH (1㎍/kg), clonidine (150㎍/m2) and Resular insulin (0.1U/kg, subcutaneously), to obese subjects and...
Packed Red Cell Transfusion in Neonate : Effects of Age of Red Cells on Serum Laboratory Values and Readjustment of Hematocrit Values after Transfusion
Dong Ha Lee, Jin Kyung Kim, Heng Mi Kim
Clin Exp Pediatr. 1994;37(4):452-456.   Published online April 15, 1994
Sick neonates often require periodic small volume transfusion(10mg/kg) to replace blood draw for laboratory monitoring during their hospital stay. The effect of packed red cell transfusion on the hematocrit, potassium, ionized calcium, acid base status, glucose and indirect bilirubin was investigated in 25 transfusions. Analysis of transfused blood by the age of the red cells, older red cells (more than...
Tc-99m HMPAO Brain SPECT in a Patient with Neonatal Seizure and Right Cerebral Hemiatrophy
Hye Young Kang, Kook In Park, Ran Namgung, Chul Lee, Chang Jun Coe, Dong Gwan Han, Tae Sub Chung, Woo Hee Jung
Clin Exp Pediatr. 1994;37(3):397-404.   Published online March 15, 1994
Functional brain imaging is very important in the diagnosis and evaluation of the various neurologic disorders. In addition to electroencephalography (EEG) and positron emission tomography (PET), single photon emission computed tomography (SPECT) have increasingly gained importance in determination of disturbances in regional brain functions. Both ictal and interictal Tc-99m hexamethyl-propyleneamine oxime single photon emission computed tomography (Tc-99m HMPAO SPECT) was done...
Clinical Analysis of 29 Cases of Germ Cell Tumor in Children
Tae Geun Song, Gyeong Ah Lee, Jae Sun Park
Clin Exp Pediatr. 1994;37(3):390-396.   Published online March 15, 1994
Germ cell tumors(GCT) are not infrequently encounted tumor in pediartic age group. In order to study the clinical behaviors of the disease, we reviewed 29 cases of GCT diagnosed and treated at Kosin Medical Center in the period of 7 years from Jan. 1984 to Dec. 1991 and the results are summarized as follows: 1) The age distriution is the highest...
Clinical analysis of Serum and Urine N-Acetyl-β-D-Glucosaminidase (NAG) in Renal Disease
Yo Han Chung, In Seok Lim, Chul Ha Kim, Byoung Hoon Yoo, Tae Sub Shim
Clin Exp Pediatr. 1994;37(3):383-389.   Published online March 15, 1994
Recently, NAG activity has gained increasing importance as an aid in the diagnosis of renoparenchymal diseases. Elevation of urine NAG activity has been found to be an indicator of renoparenchymal diseases. To evaluate the diagnostic value of the NAG activity test in the renal disease, we carried out clinical study on 31 cases of renal disease patients who had been...
Hypophosphatemic Rickets
Jae un, June Huh, Il Soo Ha, Hae Il Cheong, Yong Choi
Clin Exp Pediatr. 1994;37(3):376-382.   Published online March 15, 1994
The clinical data of 27 patients with hypophosphatemic rickets treated with phosphate and 1 α-hydroxyvitamin D were analysed retrospectively. The median age at diagnosis was 4 years, and the main clinical manifestations were bowleg and short stature. Among total 24 families, 5 families(21%) had X-linked dominant mode of inheritance, 1 family (4%) had autosomal dominant mode and 17 families (71%)...
The Effect of Long-term Phenobarbital Administration on the Bone Mineral Density of Children
Yoon Suck Suh, Young Guk Kim, Jung Hwa Lee, Kee Hwan Yoo, Joo Won Lee, Young Chang Tockgo
Clin Exp Pediatr. 1994;37(3):368-375.   Published online March 15, 1994
The long term administration of anti-convulsants on children with convulsive disorders may cause osteomalacia, depending on the dosage, duration, type and combination of anti-convulsants administred. Fifteen children, comprising 10 male and 5 female, dignosed with convulsive disorders and administered with phenobarbital for a long term period of more than 9 months but less than 84 months and 15 healthy children...
Coxiella Burnetii Infection In Patients With Various Diseases
Kyo Sun Kim, Won Young Lee
Clin Exp Pediatr. 1994;37(3):356-367.   Published online March 15, 1994
Coxiella burnetii(C. burneii) was first recognzed as the agent of Q fever in 1937. Q fever is an acute self-limited febrile illness. However, it manifests with several clinical symptoms depending upon the organs that are involved. The association of C. burnetii with human neoplasia has been rarely reported. We prospectively studied the 55 patients with fever of unknown origin, pneumonia, hepatos-plenomegaly,...
Clinical Observation of Neonatal Group B β-Hemolytic Streptococcal Meningiti
Yeon Chung Chung, Mi Won Kim, Yong Kyu Lee, Yun Jong Kang, Jung Wan Seo, Jin Keun Chang
Clin Exp Pediatr. 1994;37(3):347-355.   Published online March 15, 1994
Neonatal meningitis caused by the Group Bβ-hemolytic streptococcus was first reported in 1958. In recent years this organism has assumed major importance in the etiology of neonatal infection. In Korea, this organism is likely to play an increasing role in neonatal infection. So this investigation was designed to report the 9 cases of Group B β-hemolytic streptococcus infected neonates admitted to...
The Effect of Alfacalcidol in the Treatment of Idiopathic Myelofibrosis in Children
Soon Ki Kim, Jeong Hee Kim, Dae Hyun Lim, Jong Woon Choi, Byong Kwan Son, Hyo Seop Ahn
Clin Exp Pediatr. 1994;37(3):339-346.   Published online March 15, 1994
Idiopathic myelofibrosis (IMF), which is characterized by marrow fibrosis, leukoerythroblastic anemia, teardrop poikilocytosis and splenomegaly due to extramedullary hematopoiesis, has known to have no form of therapy. On the ground of the possibility of reversing collagen deposition in IMF using 1, 25-dihydroxycholecalciferol [1, 25(OH)2D3], we report here our observations of 5 patients (M:F = 1:4) with IMF before and after treatment...
The Metabolic Acidosis and Clinical Outcome in Acute Infantile Diarrhea
Ae Yeon Lim, Yo Ahn Rho, Kee Hwan Yoo, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 1994;37(3):332-338.   Published online March 15, 1994
To determine the types of metabolic acidosis using anion gap in acute infantile diarrhea and to correlate it with clinical outcome, we examined 103 infants admitted with acute diarrhea. The serum electrolytes (sodium, potassium, chloride, phosphorus), creatinine, CO2 content and anion gap were measured on first admission day. They were classified group A with normal anion gap (8~16 mEq/L) and...
Hypercalciuria in High Risk Neonate
Eun Sun Kim, Seung Joo Lee
Clin Exp Pediatr. 1994;37(3):322-331.   Published online March 15, 1994
The incidence and risk factors for hypercalciuria were studied in 23 sick preterm (Group I), 36 well preterm (Group II), 16 sick term (Group III) and 41 well term (Group IV) neonates who were admitted to NICU and nursery of Whwa Woman's University Hospital from May 1988 to February 1992. The results were as follows: 1) The incidences of hypercalciuria were 73.9%...
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