- Review Articles
- Nephrology (Genitourinary)
- Neonatal hypertension: concerns within and beyond the neonatal intensive care unit
- Kathleen Altemose, Janis M. Dionne
- Clin Exp Pediatr. 2022;65(8):367-376. Published online May 30, 2022
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Some neonates, especially those who are premature, may experience hypertension while in the neonatal intensive care unit (NICU). The most common causes are prematurity-related and the hypertension usually resolves over the first 1–2 years of life. Unfortunately, the increasing population of NICU graduates is at risk for later cardiovascular and kidney disease in childhood and adulthood. This population requires careful attention to blood pressure and weight throughout their life course.
- Infection
- Therapeutics for the treatment of coronavirus disease 2019 in children and adolescents
- Soo-Han Choi, Jae Hong Choi, Ki Wook Yun
- Clin Exp Pediatr. 2022;65(8):377-386. Published online June 27, 2022
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· Children and adolescents with high risks for severe coronavirus disease 2019 (COVID-19) should be identified and proper treatment should be provided promptly according to the patient’s condition.
· Remdesivir can be considered for pediatric patients of all ages with COVID-19 who have an emergent or increase in supplemental oxygen.
· The use of corticosteroids is not recommended for patients with nonsevere COVID-19. Corticosteroids are recommended in children and adolescents with severe and critical COVID-19.
- Neurology
- Neonatal seizures: diagnostic updates based on new definition and classification
- Eun-Hee Kim, Jeongmin Shin, Byoung Kook Lee
- Clin Exp Pediatr. 2022;65(8):387-397. Published online April 4, 2022
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· Neonatal seizures are often electrographic-only seizures without clinical signs; therefore, the identification of electrical seizure activity on electroencephalography is the gold standard for diagnosis.
· Clinical signs of neonatal seizures are divided into motor or nonmotor seizures, and motor seizures are mostly focal or multifocal.
· Most neonatal seizures are caused by acute symptomatic etiologies, but in cases of intractable seizures, structural, genetic, or metabolic etiologies should be investigated.
- Editorials
- Cardiology
- Early echocardiographic screening for subclinical myocardial dysfunction in children and adolescents with dyslipidemia: why and when?
- Hyun Gyung Lee, Hwa Jin Cho
- Clin Exp Pediatr. 2022;65(8):398-400. Published online March 7, 2022
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Dyslipidemia contributes to early atherosclerosis, premature cardiovascular disease, and subclinical ventricular dysfunction in children. This paper highlights the need for echocardiographic evaluation for impaired diastolic function of both ventricles and narrowing of the aortic valve and sinus of Valsalva. Therefore, early echocardiographic screening of children with primary hyperlipidemia should be considered.
- Pulmonology
- Now lung ultrasound has been established as a fundamental examination in pediatric respiratory diseases
- Kyunghoon Kim
- Clin Exp Pediatr. 2022;65(8):401-402. Published online July 13, 2022
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· Several studies demonstrated the usefulness of lung ultrasound in pediatric respiratory diseases including coronavirus disease 2019.
· Knowledge of lung ultrasound is increasing, and lung ultrasound has been established as a fundamental diagnostic examination for pediatric respiratory diseases.
- Neonatology (Perinatology)
- Factors to consider before implementing telemedicine protocols to manage neonatal jaundice
- Heui Seung Jo
- Clin Exp Pediatr. 2022;65(8):403-404. Published online April 12, 2022
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In the rapidly changing environmental situation during the coronavirus disease 2019 outbreak, neonatal centers have developed telemedicine systems with extended coverage for neonatal monitoring and high-risk follow-up programs including neonatal hyperbilirubinemia. At this point, electronic health technology and noncontact medical system increase the effectiveness of rather than replacing the face-to-face visit and the opinions of experienced neonatologists.
- Original Articles
- Hematology
- Effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major: a single-center study
- Mahmoud A. El-Hawy, Nagwan Y. Saleh
- Clin Exp Pediatr. 2022;65(8):405-409. Published online June 7, 2022
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Question: What is the effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major?
Finding: The dual-energy x-ray absorptiometry scan findings of children with β-thalassemia major and osteoporosis were improved after pamidronate administration.
Meaning: Cyclic pamidronate effectively treated osteoporosis in children with β-thalassemia major.
- Cardiology
- Early myocardial functional abnormalities in primary dyslipidemia: clinical and echocardiographic observations in young children from a highly consanguineous population
- Nehal M. El-koofy, Aya M. Fattouh, Areef Ramadan, Mohamed A. Elmonem, Dina H. Hamed
- Clin Exp Pediatr. 2022;65(8):410-416. Published online December 8, 2021
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In children with primary dyslipidemia, functional myocardial abnormalities can occur at young age, including diastolic functional impairment of both ventricles and narrowing of the aortic valve and the sinus of Valsalva. Echocardiographic evaluations of high-risk children may be as important as biochemical evaluations.
- Retraction Notice
- Coronavirus disease 2019 in a 2-month-old male infant: a case report from Iran
- Hosein Heydari, Seyed Kamal Eshagh Hossaini, Ahmad Hormati, Mahboubeh Afifian, Sajjad Ahmadpour
- Clin Exp Pediatr. 2022;65(8):417-417. Published online July 19, 2022
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