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Volume 41(10); Oct 1998
Clinical Lecture
Chronic Diarrhea in Childhood : Diagnosis and Treatment
J Korean Pediatr Soc. 1998;41(10):1317-1323.   Published online October 15, 1998
Original Articles
Thyroid Hormone Concentrations in Preterm Infants
Sung Keun Moon, Jeong Nyun Kim, Mi Jung Park, Myung Jae Choi, Chrul Young Chung
J Korean Pediatr Soc. 1998;41(10):1324-1328.   Published online October 15, 1998
Purpose : To establish reference ranges for thyroid hormone concentrations in premature infants, we measured T4 and thyroid stimulating hormone(TSH) concentrations and analyzed the relation to gestational age and birth weight. Methods : Serum T4 and TSH concentrations were measured by radioimmunoassay for 391 premature infants born in Sanggye Paik Hospital for two years and eight months. Results : Gestational age of...
Clinical Effect of Bronchoalveolar Lavage in Ventilated Preterm Infants
Hyeon-Soo Lee
J Korean Pediatr Soc. 1998;41(10):1329-1333.   Published online October 15, 1998
Purpose : Bronchoalveolar lavage(BAL) in ventilated neonates is a modification of routine endotracheal suction and is a potentially useful technique in studying the evolution and resolution of pulmonary inflammation. Therefore, this study is designed to investigate the effects of BAL on blood gases, blood pressure and heart rate in ventilated newborn infants with respiratory disease. Methods : Fourteen premature infants were...
Comparison of Treatment Course and Outcome between Medically and Surgically Treated Patent Ductus
Jeong Geun Kim, Jeong Nyun Kim, Dong Chul Park, Shin Yeong Lee, Hyun Chul Lee, Myung Jae Chey, Churl Young Chung,
J Korean Pediatr Soc. 1998;41(10):1334-1341.   Published online October 15, 1998
Purpose : Early intervention is needed to treat patent ductus arteriosus(PDA) as it is a major cause of increased mortality in preterm infants. However, it is uncertain which is better, medical versus surgical management. We reviewed medical records to compare the treatment course and outcome between medically and surgically treated preterm PDA infants. Methods : Thirth-two Mechanically ventilated pretem infants(gestational age<34...
Immunologic Changes of HL-60 Cells by Differentiation Inducing Agents I : Phenotypic Differentiation of FcγR and Mac-1
Hye Soon Kim, Kyung Hyo Kim, Gyoung Hee Kim, Ju Young Seoh
J Korean Pediatr Soc. 1998;41(10):1342-1350.   Published online October 15, 1998
Purpose : Fc receptors and Mac-1 play an important role in the protective response of granulocytes and monocytes against microbial infection. FcγRⅠ, FcγRⅡ, FcγRⅢ as well as CD11b/ CD18 have never been measured in a quantitative way during hemopoiesis. Thus we quantified the expression of FcγRⅠ, FcγRⅡ, FcγRⅢ, and CD11b/CD18 during hematopoietic differentiation using HL-60 cells, which was induced to...
The Diagnostic Value of Polymerase Chain Reaction in Mycoplasma pneumoniae Pneumonia
Han Wook Kang, Byung Moon Ahn, Moo Young Song, Eun Ryoung Kim, Suk Ho Choi, Il Soo Kim
J Korean Pediatr Soc. 1998;41(10):1351-1358.   Published online October 15, 1998
Purpose : This study was performed to evaluate the polymerase chain reaction(PCR) in the diagnosis of Mycoplasma pneumoniae pneumonia in comparison with the specific antibody test. Methods : Five hundred and ten patients with pneumonia, ranging from the ages of 8 months to 15 years who were admitted in Sung-Ae and Kwangmyung Sung-Ae general hospitals from Nov. 1996 to Oct....
Clinical Features and Endoscopic Findings of Helicobacter pylori Infection in Children
Seon Hee Kim, Cheol Ho Chang, Churl Young Chung
J Korean Pediatr Soc. 1998;41(10):1359-1364.   Published online October 15, 1998
Purpose : Helicobacter pylori(H. pylori) is recognized as the cause of primary or unexplained gastrointestinal diseases in children as well as in adults. However, it is unclear whether H. pylori causes specific clinical symptoms or diseases. Therefore, we studied the clinical manifestations associated with H. pylori infection in consecutive symptomatic children undergoing diagnostic endoscopy. Methods : This study included 42...
Clinical Application of a Scoring System in the Diagnosis of Group A Streptococcal Pharyngitis
Hyeon-Bu Kim, Byung-Soo Cho, Sung-Ho Cha, Jeong-Hun Ha, Sun-Hee Kim, Gui-Sook Cho
J Korean Pediatr Soc. 1998;41(10):1365-1371.   Published online October 15, 1998
Purpose : A scoring system could be clinically useful in determining cases in which a throat culture may be omitted or in cases whether antibiotics may be initiated or not. We propose to make a clinical guideline of antibiotics administration in patients with pharyngitis. Methods : From Apr. 1996. to Mar. 1997, throat cultures were taken from 321 cases(72 cases from...
Clinical and Pathological Comparison of Neonatal Hepatitis and Extrahepatic Biliary Atresia in Korean Children
Jae Hong Park, Ju Suk Lee, Su Eun Park, Chang Hun Lee
J Korean Pediatr Soc. 1998;41(10):1372-1379.   Published online October 15, 1998
Purpose : Neonatal hepatitis and congenital extrahepatic biliary atresia are two major causes of neonatal cholestasis. But the method of therapeutic trials used for each disease is essentially different. Nonetheless, it is very difficult to differentiate these diseases clinically and histologically. This study is aimed to find out major differences between the two by clinical characteristics and scoring of various...
Developmental Changes of Spectral and Chaotic Indexes of Heart Rate Variability in Normal Fetuses
Jee-Young Jung, Myung-Kul Yum, Nam-Su Ki, Jae-Won Oh, Chang-Ryul Kim, Jung Hye Hwang, Moon-Il Park
J Korean Pediatr Soc. 1998;41(10):1380-1388.   Published online October 15, 1998
Purpose : The purposes of this study were to determine the normal values of spectral and chaotic indexes and to assess the maturational process of autonomic and chaotic control of fetal heart rate according to gestational age. Methods : Three hundred and thirty-seven mothers with normal singleton pregnancies, who were 23 weeks or more in gestational age, was randomly chosen. For...
Diagnostic Method of Congenital Cardiovascular Diseases Using Spiral Computed Tomography and Three Dimensional Reconstruction
Hye Kyung Lee
J Korean Pediatr Soc. 1998;41(10):1389-1396.   Published online October 15, 1998
Purpose : One of the new methods for diagnosing congenital cardiovascular diseases is the spiral CT and three-dimensional image reconstruction. The spiral CT allows continuous data collection while the subject is advanced through the CT gantry, it provides an uninterrupted volume of data that can be reconstructed to produce a three-dimensional representation of CT information and also this method has...
The Effect of Steroid Therapy on Growth and Bone Density in Children with Nephrotic Syndrome
Seong Hoi Jeon, Ae Yeon Lim, Young Kook Kim, Hae Won Cheon, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
J Korean Pediatr Soc. 1998;41(10):1396-1402.   Published online October 15, 1998
Purpose : Long-term steroid therapy for various glomerular disorders in children has been known to decrease serum Vit D3 level and develop osteomalacia. The aim of this study was to observe the effect of long-term steroid therapy on growth and bone density in children with nephrotic syndrome. Methods : Bone density of 17 steroid-treated nephrotic syndrome was compared with that of...
Study on Serum Level of Phenobarbital after Intravenous Administration of Loading Dose
Eun Young Park, In Joon Seol
J Korean Pediatr Soc. 1998;41(10):1403-1410.   Published online October 15, 1998
Purpose : To learn the changes of phenobarbital serum level after intravenous administration of loading dose and to determine the optimal time of maintenance therapy to support therapeutic concentration. Methods : A total of 24 patients, who were admitted to the pediatric ward for treatment of ongoing and recurrent seizure, were enrolled in this study from November, 1994 to August,...
The Clinical Study on Marfan Syndrome
Jung Sim Kim, Dong Kyu Jin, See Hwan Ko, Jee Yeon Min, I-Seok Kang, Kye Won Jeon, Yung Lan Choi, Heung Jae Lee, Seung Woo Park, Won Ro Lee, Chong Suh Lee, Sei Yeul Oh, Chang Won Ki, Han Wook Yoo, In Sook Park, Jae Kon Ko
J Korean Pediatr Soc. 1998;41(10):1411-1416.   Published online October 15, 1998
Purpose : The aim of this study was to assess the involvement of several organs patients with Marfan syndrome in Korea. Also the clinical features in childhood patients with Marfan syndrome were assessed. Methods : Thirty-eight cases of Marfan syndrome were enrolled in this study. Clinical evaluations of the musculoskeletal, cardiovascular and occular system were performed in all cases. Results : The...
Case Reports
A Case of Pulmonary Artery Sling Associated with Left Bronchial Stenosis and Patent Ductus Arteriosus
Woo Suk Juhng, Myung Hee Han, Chan Uhng Joo
J Korean Pediatr Soc. 1998;41(10):1417-1423.   Published online October 15, 1998
Pulmonary artery sling is a rare and potentially lethal vascular anomaly wherein the anomalous left pulmonary artery arises from the posterior aspect of the right pulmonary artery and passing to the left lung between the trachea and the esophagus which causes respiratory distress in infants and children due to the extrinsic compression of the airway by the anomalous vessel. Associated...
A Case of Congenital Self-Healing Reticulohistiocytosis
Taek Sun Kim, Chang Wan Kim, Eun Ryoung Kim, You Mee Kang, Kye Yong Song
J Korean Pediatr Soc. 1998;41(10):1424-1429.   Published online October 15, 1998
Congenital self-healing reticulohistiocytosis(CSHR) is a rare variant of cutaneous reticulohistiocytosis. We report a newborn who had about 25 reddish brown papulonodular lesions on whole body at birth. No extracutaneous involvement was found. All skin lesions involuted within 4 months spontaneously. Biopsy of a skin lesion showed marked aggregated histiocytic infiltration with some eosinophils. S-100 protein and lysozyme were positive. Electron...
A Case of Inappropriate ADH Secretion Secondary to Vinblastine Therapy
Eun-Hye Park, Hyun-Sang Cho, Hae-Sook Yoo, Chuhl-Joo Lyu, Chang-Hyun Yang, Kir-Young Kim
J Korean Pediatr Soc. 1998;41(10):1430-1432.   Published online October 15, 1998
Inappropriate secretion of antidiuretic hormone(ADH) secondary to vincristine therapy has been reported frequently. But there has been five previous reports of vinblastine associated SIADH in the world and in 4 reports, bleomycin and cis-platinum were used along with vinblastine together. Because penetration of vinka alkaloids into CSF of humans is known to be poor, it has been suggested that lowering...
A Case of Williams Syndrome Diagnosed by FISH
Hyun Kim, Won Bae Lee, Won Bae Lee
J Korean Pediatr Soc. 1998;41(10):1433-1437.   Published online October 15, 1998
Williams syndrome was first reported in 1961, it is characterized by distinct facial changes, growth deficiency, mental retardation, congenital heart defect(particularly the supravalvular aortic stenosis), associated at times with infantile hypercalcemia. The diagnosis of this disease relied on phenotype, after recent acknowledgement of its genetic basis on the 7th chromosomal locus q11.23 involving elastin gene on the PCR. Recently, commercial...
A Case of Ectopic Pancreas with Malrotation
Il Song Kang, Kil Soo Chung, Jae Kook Cha, Kon Hee Lee, Kwan Seop Lee, Byung Chun Kim, Eun Sook Nam
J Korean Pediatr Soc. 1998;41(10):1438-1441.   Published online October 15, 1998
Ectopic pancreas is defined as pancreatic tissue lacking anatomical and vascular continuity with the main body of the pancreas. Common symptoms are epigastric pain, hemorrhage, chest pain, weight loss, nausea and vomiting. A 2-month-old male patient was hospitalized because of continuous bile stained vomiting for 2 days. Abdominal ultrasonography and colon study showed malrotation of the intestine. Surgical exploration revealed...
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