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Original Article
Respiratory syncytial virus-associated seizures in Korean children, 2011–2016
Teahyen Cha, Young Jin Choi, Jae-Won Oh, Chang-Ryul Kim, Dong Woo Park, In Joon Seol, Jin-Hwa Moon
Clin Exp Pediatr. 2019;62(4):131-137.   Published online October 23, 2018

Purpose: Respiratory syncytial virus (RSV) infection can cause various neurological complications. This study aimed to investigate the RSV-associated neurologic manifestations that present with seizures. Methods: We retrospectively reviewed the medical records of patients aged less than 15 years with laboratory-confirmed RSV infections and seizures between January 2011 and December 2016 in a regional hospital in South Korea. Results: During this period, 1,193...
Case Report
A new mosaic der(18)t(1;18)(q32.1;q21.3) with developmental delay and facial dysmorphism
Young-Jin Choi, Eunsim Shin, Tae Sik Jo, Jin-Hwa Moon, Se-Min Lee, Joo-Hwa Kim, Jae-Won Oh, Chang-Ryul Kim, In Joon Seol
Clin Exp Pediatr. 2016;59(2):91-95.   Published online February 29, 2016

We report the case of a 22-month-old boy with a new mosaic partial unbalanced translocation of 1q and 18q. The patient was referred to our Pediatric Department for developmental delay. He showed mild facial dysmorphism, physical growth retardation, a hearing disability, and had a history of patent ductus arteriosus. White matter abnormality on brain magnetic resonance images was also noted....

Original Article
Medicolegal Problems in Pediatric Area
Soo Jeong Kwon, Ji Young Jang, Nam Su Kim, Myung Kul Yum, In Joon Seol, Ku Won Jung
Clin Exp Pediatr. 2005;48(8):813-819.   Published online August 15, 2005
Purpose : Medicolegal problems start when the patient asserts the mistake of doctor and doctor does not accept it. The purpose of this study is to assess the actual condition of medicolegal problems and to provide solutions of medicolegal problems in the pediatric field. Methods : There is not official statistical data about medicolegal problems in our country. We gathered...
Case Report
A Case of Sandifer Syndrome
Mira Lee, Soo Hyun Kim, Yong Joo Kim, In Joon Seol
Clin Exp Pediatr. 2003;46(10):1036-1039.   Published online October 15, 2003
Sandifer syndrome is a rare manifestation of gastroesophageal reflux in children, occurring in association with abnormal movement of the head and neck and recurrent episodes of seizure after feeding. This syndrome may be misdiagnosed as infantile seizure and musculoskeletal disorder and may be associated with failure to thrive, anemia, aspiration pneumonia, and esophagitis. In this paper, Sandifer syndrome in a...
Original Article
The Usefulness of Emergency Brain Computerized Tomography in Children with First Seizures
Hyun Kyung Park, In Joon Seol
Clin Exp Pediatr. 2001;44(5):562-568.   Published online May 15, 2001
Purpose : This study was performed to discover whether emergency brain computerized tomography(CT) is useful for the diagnosis and management of patients with first seizure. Methods : We studied retrostpectively all children(under 15-year-old) without a history of neurologic illness who visited Hanyang University Hospital and took a brain CT because of a first seizure attack between January 1996 and June 1999....
Case Report
A Case of Atypical Benign Partial Childhood Epilepsy
Hae Jung Park, In Joon Seol
Clin Exp Pediatr. 2001;44(2):211-215.   Published online February 15, 2001
We report a case of atypical benign partial childhood epilepsy in a 11 years old male child whose case has been followed up for 6 years. His first symptom was focal seizure of the left side of his face during a drowsy state, followed by focal seizures of left fingers and legs. At that time he had been on phenobarbital...
Original Article
A Study on the Clinical Significance of Periodic Lateralized Epileptiform Discharges and Relation to Brain Imaging Study in Children
Jong Hwa Lee, Eun Young Park, Nam Su Kim, In Joon Seol
Clin Exp Pediatr. 2000;43(3):380-385.   Published online March 15, 2000
Purpose : Periodic lateralized epileptiform discharges(PLEDs), initially described by Chatrian et al in 1964, are an EEG phenomenon characterized by lateralized or focal spike-and-wave complexes with moderate to high voltage which occur in a periodic or semiperiodic pattern. This study was performed to assess the clinical significance of PLEDs and its relation to an imaging study of the brain. Methods :...
Study on Serum Level of Phenobarbital after Intravenous Administration of Loading Dose
Eun Young Park, In Joon Seol
Clin Exp Pediatr. 1998;41(10):1403-1410.   Published online October 15, 1998
Purpose : To learn the changes of phenobarbital serum level after intravenous administration of loading dose and to determine the optimal time of maintenance therapy to support therapeutic concentration. Methods : A total of 24 patients, who were admitted to the pediatric ward for treatment of ongoing and recurrent seizure, were enrolled in this study from November, 1994 to August,...
A Study on the Serum Level of Phenytoin after Intravenous Administration of Loading Dose
In Joon Seol, Young Iee Yu
Clin Exp Pediatr. 1997;40(10):1435-1442.   Published online October 15, 1997
Purpose : Phenytoin is effectively and widely used drug for the treatment of status epilepticus and patient with ongoing seizure by intravenous infusion. It is generally recommended to maintain serum concentration above 10μg/ml for the sustained effective anticonvulsant effect. This study was designed to know the optimal time to begin oral maintenance therapy after initial intravenous infusion. Methods : Total 17 patients with status epilepticus...
Case Report
A Case of Cerebral Infarction Associated with Mycoplasma pneumoniae Infection
Young Jae Koh, Dong Jun Kim, In Joon Seol, Ha Baik Lee, Ki Woong Hong
Clin Exp Pediatr. 1996;39(1):115-119.   Published online January 15, 1996
Mycoplasma pneumoniae has been shown to be of etiologic importance in cases of upper-and lower-respiratory tract infections, especially in children and young adults. It may cause a variety of extrapulmonary manifestations in multiple organ systems, most commonly the central nervous system. The extrapulmonary syndromes include meningitis, cerebral infarction, acute transverse myelitis, psychosis, cerebellar ataxia, Guillain-Barré syndrome and Reye syndrome. Cerebral...
Original Article
A Study on the Necessity to Revise the Present Growth Data for Height and Weight? -Base on Data from the Circumference and Triceps Thickness-
Gi Dong Hwang, Jae Kyung Choi, Jeh Hoon Shin, Nam Soo Kim, In Joon Seol, Hahng Lee
Clin Exp Pediatr. 1995;38(6):745-751.   Published online June 15, 1995
Purpose : Applying the present growth curve(established in 1985) in practice, we noticed some difference. And so, we performed this study to know that is it necessary to revise the present standard data in Korea. Methods : We checked the height and weight of 208 children of one primary school in Seoul. And also, we measured arm circumference and triceps thickness...
Case Report
A Case of Defecation-induced Epilepsy
Dong Nam Kim, In Seung Park, In Joon Seol
Clin Exp Pediatr. 1995;38(1):138-140.   Published online January 15, 1995
Defecation induced epilepsy is a very rare form of reflex epilepsy, which has not been reported yet in Korea. We experienced a case of defecation-induced epilepsy in a 10 month old boy who has been showing seizure with every defecation since 5 months of his age. Diagnosis was made by clinical history and appearance of clinical seizure with epileptiform activities...
Original Article
A Study on Prognostic Factors in Children with Encephalopathy
Jin Nyoung Park, In Joon Seol
Clin Exp Pediatr. 1994;37(12):1738-1745.   Published online December 15, 1994
To elucidate the clinical characteristics-especially its clinical pattern and outcome of chidren with encephalopathy, we carried out a retrospective review on medical records of 45 patients who were intially diagnosed as encephalopathy except mumps meningitis, Reye's syndome and neonatal hypoxic ischemic encephalopathy at the Department of pediatrics, Hanyang University children's hospital from January 1986 to February 1994. The results were summerized...
The Study on the Clinical Significance of the Finger Extension Reflex in Early Infancy
Seong Yeob Moon, In Joon Seol
Clin Exp Pediatr. 1994;37(10):1350-1356.   Published online October 15, 1994
The finger extension reflex was performed to the 419 normal infants without CNS abnormalities that visited to the well baby clinic and out-patient department, and so to the patients with CNS abnormalities on the brain sonography and brain CT under the age of 2 months from May 1992 to September 1993 in the department of pediatrics, Hanyang university hospital. The results...
Occult Mediastinal Ganglioneuroblastoma Presenting with Myoclonic Encephalopathy as Paraneoplastic Syndrome
Hahng Lee, Dong Ki Han, Jae Won Oh, In Joon Seol, Eun Kyung Hong, Seok Chol Jeon
Clin Exp Pediatr. 1994;37(5):695-700.   Published online May 15, 1994
Ganglioneruroblastoma and neuroblastoma are among commonest types of childhood malignancy and a number of unique paraneoplastic syndromes have been associated with both localized and disseminated neuroblastoma. The coincidence of neuroblastoma and myoclonic encephalopathy or other paraneoplastic syndromes occurs relatively rare, and therefore, failure to recognize this association could result in delays in both diagnosis and treatment, and the result...
Case Report
A Case of Rotor Syndrome
Jin Nyoung Park, In Joon Seol
Clin Exp Pediatr. 1994;37(3):410-415.   Published online March 15, 1994
We experienced a case of Rotor syndrome in an 8 year 6 month old boy who presented with icteric sclera and icteric skin on whole body. His clinical and laboratory characteristics were as follows; 1) Jaundice appeared from several months ago before admission without any clinical disturbance. 2) Direct bilirubin was more increased than indirect bilirubin. 3) Plasma indocyanine green (ICG) kinetics test...
Original Article
Clincal Observation on Guillain-Barré Syndrome in Children
In Cheol Park, In Seung Park, Jeh Hoon Shin, In Joon Seol, Ha Baik Lee
Clin Exp Pediatr. 1993;36(5):634-642.   Published online May 15, 1993
Clinical observation was performed on 23 children with Guillain-Barré syndrome which were hospitalized at the Pediatric ward of Han Yang University Hospital, from July 1975 through May 1991. The results were as follows: 1)The ratio of male patient to female was 2.8:1 and 47.8% of total GBS patients were between the ages 1to 5 years. 2)The highest seasonal incidence of GBS was seen...
Study on the Frequency of Right Bundle Branch Block After Surgical Closure of Ventricular Septal Defect
Ho Joon Im, Jin Nyoung Park, Nam Su Kim, Jeh Hoon Shin, In Joon Seol, Soo Ji Moon
Clin Exp Pediatr. 1993;36(1):88-93.   Published online January 15, 1993
The purpose of this study is to evaluate the ventricular conduction abnormalities, especially RNNN, observed electrocardiographically after sugical closure of VSD. The present study population consists of 92 patients with VSD who were surgically corrected at the Hanyang University Hospital during 6 years period from Jan. 1985 to Dec. 1990. We reviewed their clinical records including surgical notes and EKG findings...
Case Report
A Case of Video Game Epilepsy
Jin Nyoung Park, Ho Joon Im, Sung Lae Park, Jeh Hoon Shin, In Joon Seol, Soo Ji Moon
Clin Exp Pediatr. 1992;35(12):1756-1761.   Published online December 15, 1992
Video game epilepsy is a photic induced sensory evoked seizure, and the seizure occurs only following a specific program of video game. We experienced a case of video game epilepsy in a 12 year old boy who presented with seizure during video game, and showed photoconvulsive response on photic stimulated EEG.
A Case of Salmonella Group C Meningitis
Dae Chul Kim, Ju Hyun Han, So Young Lee, Jeh Hoon Shin, In Joon Seol
Clin Exp Pediatr. 1992;35(10):1449-1453.   Published online October 15, 1992
We experienced a case of salmonella group C meningits in a 3 month old male. His initial chief complaints at the admission were high fever, lethargy, irregular respiration and arrythmias. Diagnosis was confirmed by lumbar puncture, blood culture and CSF culture. Ceftriaxone was used and recovered with some sequelae such as irritability, generalized spasticity and mild regression of psychomotor development.
A Case of Neuronal Ceroid-Lipofuscinosis with characterstic photic evoked spikes in EEG
Joo Hyun Han, Jae Won Oh, Jae Hoon Shin, In Joon Seol, Young Hyae Koh, Moon Hyang Park
Clin Exp Pediatr. 1992;35(2):252-256.   Published online February 15, 1992
We experienced a case of neuronal ceroid lipofuscinosis in a 1 year old female child. Her chief complaints on admission were retarded growth and development, recurrent seizures and hypotonia. Electroencephalographic examination showed very characteristic photic responses, so called, photic evoked spikes which are synchronous with the flashes at 5 flashes per second. Final diagnosis was made with electron microscopic examination of...
Original Article
Clinical Study of Group B Streptococcal Infection in Infants Less Than Two Months of Age
Hee Jeong Ahn, Ji Yeon Lim, Sung Hee Oh, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1992;35(1):17-25.   Published online January 15, 1992
Since 1970, the group B streptococcus has become significant cause of neonatal septicemia and/or meningitis, in recent years the group B streptococcus and E.coli are most common etiologic agent of septicemia and/or meningitis in infants less than two months of age. We have analized 8 cases of group B streptococcal infection who admitted to the department of Pediatrics, Hanyang University...
A clinical study on twin.
Ho Joon Im, Sang Yoon Ahn, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1991;34(5):621-628.   Published online May 31, 1991
Among the total of 17,991 newborns delivered at Hanyang University Howpital from January 1980 to December 1989, a clinical study was performed on 277 twin pregnancies. The results of the study were as follows: 1) The incidence of twins was 1:64.9. 2) The average male-female sex ratio of twins was 1:1.1, total same sex pairs rate was 79.4% (male-male & female-female) and different sex rate was 20.6%. 3) The...
A case of report fiber syndrome.
So Young Lee, Sun Yang Hong, Jae Hoon Shin, In Joon Seol
Clin Exp Pediatr. 1991;34(1):115-119.   Published online January 31, 1991
This is a report of 10 years old boy whose complete total ophthalmoplegia, ataxia and areflexia (Fisher syndrome) were the outstanding clinical features.
A case of interstitial pulmonary fibrosis.
Hak Won Kim, Ho Joon Im, In Joon Seol, Ha Baik Lee, Hahng Lee, Seok Chol Jeon, Moon Hyang Park
Clin Exp Pediatr. 1991;34(1):107-114.   Published online January 31, 1991
Interstitial pulmonary fibrosis is a rare, diffuse lug disease which has a tendency to destroy the lung architectures by consequent healing with progressively severe fibrosis. We report with a brief review of literature, one case of a 7-year old female with the typical pictures of interstitial pulmonary fibrosis, histologically on open lung biopsy, and clinically presenting with chronic respiratory difficulty but without definite symptoms...
A clinical and Statistical study of Meconium Stained Baby: A Two Year Prospective Study.
Joo Hyun Ham, Sang Yoon Ahn, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1990;33(9):1173-1179.   Published online September 30, 1990
Among the total of 2,483 Newborns delivered at Hanyang University Hospital from January 1987 to December 1988, a clinical study was performed of meconium stained baby. The results are summerized as follows: 1) The incidence of meconium staining was 13.4% (333 cases) in total 2,483 newborns. 2) In the groups that the birth weight is 2501 ~ 4000 gm and up to 4001 gm, the incidence...
A Case of Malignant Ependymoma.
Ja Wook Koo, Sun Ho Lee, In Joon Seol, Hahng Lee
Clin Exp Pediatr. 1989;32(1):130-136.   Published online January 31, 1989
Intracranial tumors presenting in the first year of life are uncommon. Brain tumors in infancy are predominantly supratentorial, whereas in older children the majority are infratentorial. Malignant ependymoma is a rare type of primitive ependymal tumor with clinically high malignancy. We experienced a malignant ependymoma in a 5 month old girl who had progressive enlargement of head circumference with vomiting. Brain computed tomography revealed...
A Case of Paroxysmal Kinesigenic Choreoathetosis.
Jeong Kook Lee, In Joon Seol
Clin Exp Pediatr. 1989;32(1):116-120.   Published online January 31, 1989
Paroxysmal choreoathetosis is a rare, involuntary movement disorder, wich occur spontaneously or may be induced by movement, startle or anxiety. The attacks are tonic, dystonic or choreoathetotic without loss of consciousness, urinary inconti- nence, or amnesia. The atacks begin most often in school aged years and the course is nonprogressive. The response to anticonvulsant therapy is usually excellent, We report a case of paroxysmal kinesigenic choreoathetosis...
A Case of Mollaret Meningitis.
Yong Joo Kim, Soon Sup Jang, In Joon Seol
Clin Exp Pediatr. 1988;31(9):1193-1196.   Published online September 30, 1988
Mollaret meningitis is a benign recurrent aseptic meningitis. We experienced a case of Mollaret meningitis in a 5 years old male child. He has had 4 times of recurrent aseptic meningitis after antecedent viral infection which showed meningeal irritation signs, weakness of lower extremities and urination difficulties. We present a case of Mollaret meningitis with brief review of related literatures.
Lateral Ventricular Indices in tuberculous Meningitis.
Ja Wook Koo, Hang Bo Cho, In Joon Seol, soo Jee Moon, Hahng Lee, Keun Soo Lee
Clin Exp Pediatr. 1988;31(8):984-991.   Published online August 31, 1988
Computed tomography is a very valuable method by which the pathogenic evolution of tuberculous meningitis may be followed, thereby facillitating its differential diagnosis and controlling the effi- ciency of therapy, and assessing the degree of hydrocephalus. Fifteen cases of clinically proven intracranial tuberculosis were studied by lateral ventricular indices of brain computed tomography in our hospital during last 3 years. The results were as follows: 1)...
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