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Pulmonology

Benefits and risks of therapeutic alternatives for macrolide resistant Mycoplasma pneumoniae pneumonia in children

Hyeon-Jong Yang

Clin Exp Pediatr. 2019;62(6):199-205. Published online March 15, 2019

Crossref 16

Although Mycoplasma pneumoniae pneumonia (MPP) has been generally susceptible to macrolides, the emergence of macrolide-resistant MPP (MRMP) has made its treatment challenging. MRMP rapidly spread after the 2000s, especially in East Asia. MRMP is more common in children and adolescents than in adults, which is likely related to the frequent use of macrolides for treating M. pneumoniae infections in children....

DOI: https://doi.org/10.3345/kjp.2018.07367

Systemic use of fluoroquinolone in children

Soo-Han Choi, Eun Young Kim, Yae-Jean Kim

Clin Exp Pediatr. 2013;56(5):196-201. Published online May 28, 2013

Crossref 44

Fluoroquinolones are an important class of antibiotics that are widely used in adult patients because of their broad spectrum of activity, good tissue penetration, and oral bioavailability. However, fluoroquinolone use in children is limited because juvenile animals developed arthropathy in previous experiments on fluoroquinolone use. Indications for fluoroquinolone use in patients younger than 18 years, as stated by the U.S....

DOI: https://doi.org/10.3345/kjp.2013.56.5.196

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