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Original Article
A Clinical Study of the Acute Respiratory Distress Syndrome in Children
Taek Jin, Dong Soo Kim, Dong Hwan Shin
Clin Exp Pediatr. 2003;46(1):42-50.   Published online January 15, 2003
Purpose : The acute respiratory distress syndrome(ARDS), an acute form of severe alveolar-capillary injury evolving after a direct or indirect lung insult is thought to be a common cause of respiratory failure though not many clinical studies on the subject have been made yet. Methods : Between January 1992 and December 2001, we conducted a retrospective study on 33 children who...
Clinical Analysis of Acute Respiratory Tract Infections by Influenza Virus in Children
Min Kyoung Kwon, Mi Ran Kim, Eun Young Park, Kon Hee Lee, Hae Sun Yoon, Kwang Nam Kim, Kyu Man Lee
Clin Exp Pediatr. 2002;45(12):1519-1527.   Published online December 15, 2002
Purpose : Although influenza virus is one of the most important causes of acute respiratory tract infections(ARTIs) in children, virus isolation is not popular and there are only a few clinical studies on influenza in Korea. We evaluated the epidemiologic and clinical features of ARTIs by influenza virus in children. Methods : From February 1995 to August 2001, nasopharyngeal aspirations were...
The Findings and Significances of Brain SPECT in Acute Mealses Encephalitis
Jung Chul Kim, Ju Mi Choung, So Hee Eun, Dae-Yeol Lee, Jung Soo Kim
Clin Exp Pediatr. 2002;45(11):1373-1380.   Published online November 15, 2002
Purpose : Acute measles encephalitis(ME) is characterized by an abrupt onset of fever and obtundation, frequently accompanied by seizures and multifocal neurological signs. The aim of this study was to clarify the clinical manifestation, progression and the brain SPECT patterns in patients with acute ME. Methods : This study included 11 children with acute ME admitted to Chonbuk National University Hospital. Ten patients received a...
Case Report
A Case of Primary Epiploic Appendagitis
Tae Young Ha, Chi Kwan Kim, Jin Young Jeong, Jong Hwa Lee
Clin Exp Pediatr. 2002;45(8):1024-1027.   Published online August 15, 2002
Epiploic appendages are small, 0.5-5 cm long, peritoneal pouches containing small vessels and fat, located on the serous surface of the colon, from the cecum to the rectosigmoid junction. Pathologic states are rare in these appendages, the most frequent being is infarction either due to torsion or spontaneous. As a result of subsequent inflammatory reaction, the condition has been termed...
Original Article
Clinical Features of Subacute Necrotizing Lymphadenitis in Children
Ji Young Hong, Sun Hwan Bae, Wan Sup Kim
Clin Exp Pediatr. 2002;45(8):994-999.   Published online August 15, 2002
Purpose : There is a predilection for subacute necrotizing lymphadenitis(SNL) in young Asian women. Few pediatric cases have been reported. This study was performed to evaluate clinical features of children with SNL. Methods : We retrospectively analyzed clinical features of 23 cases of SNL under 15 years of age identified in Nowon Eulji Hospital from February 1995 to January 2002. Two...
Comparison of Two Rapid Antigen Detection Tests for Diagnosis of Group A Streptococcal Pharyngotonsillitis
Seung Kyu Song, Mi Ae Hong, Kyung Chang Oh, Seung In Ahn, Mi Hyon Tae, Hye Jung Shin, Jin Keun Chang, Sung Ho Cha
Clin Exp Pediatr. 2002;45(8):973-979.   Published online August 15, 2002
Purpose : Recently, a number of rapid antigen detection tests have been available to diagnose group A streptococcal pharyngotonsillitis. The purpose of this study was to determine the sensitivity, specificity and consistency of the two rapid antigen detection tests. Methods : Among the patients who visited our clinic from November 2001 to February 2002, 61 patients who had clinical findings of...
Clinical Features of Acute Scrotum in Children
Ja Yun Yun, Mi Ran Kim, Kon Hee Lee, Kwang Nam Kim
Clin Exp Pediatr. 2001;44(12):1424-1431.   Published online December 15, 2001
Purpose : The acute scrotum is a clinical syndrome that is defined as an acute, painful swelling of the scrotum or its contents. The symptoms and signs of acute scrotum are similar and its pathognomonic features are rarely detected. This study was performed to find a proper way to diagnose and treat acute scrotum promptly and correctly. Methods : From January 1990 through December...
Case Report
A Case of Wernicke's Encephalopathy which Occurred During Chemotherapy in a Child with Acute Myeloblastic Leukemia
Sang-Nam Bae, Bu-Jin Kim, Seong-Shik Park, Sang-Ook Nam, Young-Tak Lim, Hak-Jin Kim
Clin Exp Pediatr. 2001;44(11):1320-1325.   Published online November 15, 2001
Wernicke,s encephalopathy(WE), a neurological disorder caused by thiamine deficiency, is characterized by the triad of ocular symptoms, ataxia, and mental confusion. More than 90% of the cases are observed in chronic alcoholics. Other conditions less frequently associated with WE are anorexia nervosa, prolonged parenteral nutrition, hemodialysis, uremia, hyperemesis gravidarum, gastroplasty for morbid obesity, and acquired immunodeficiency syndrome(AIDS). One of the...
A Case of Acute Necrotizing Encephalopathy
Sung Kee Kim, Se Wook Oh, Young Kyoun Kim, Se Chang Ham, Yong Won Park, Sang Woo Kim
Clin Exp Pediatr. 2001;44(8):954-958.   Published online August 15, 2001
This disease predominantly affects infants and young children living in Japan and Taiwan, and manifests itself as acute encephalopathy following viral infections. The hallmark of this encephalopathy is multifocal, symmetric brain lesions affecting bilateral thalamus, brainstem tegmentum, cerebral periventricular white matter and cerebellar medulla, which can be visualized by computed tomography and magnetic resonance imaging. Both the gray and white...
Three Cases of Acute Scrotal Disorders in the Neonate
Ja Yun Yun, Min Kyoung Kwon, Mi Ran Kim, Kon Hee Lee, Kwang Nam Kim, Ho Hyun Jeong
Clin Exp Pediatr. 2001;44(7):841-846.   Published online July 15, 2001
Acute scrotal disorders(ASD) in neonates-especially the torsion of testes- are rare, and the clinical presentations are quite different from those of adolescents or adults. The neonates with ASD are generally afebrile and do not show typical symptoms. Early diagnosis and proper treatment of ASD are very important but the differentiation of torsion and orchitis is not easy in neonates. The...
Original Article
A Study of Acute Poisoning in Korean Children
Chan Sook Park, Song Hyeun Eun, Mi Hwa Yang, Jin A Son, Jung Yun Hwang, Jae Wook Ko, Don Hee Ahn
Clin Exp Pediatr. 2001;44(6):614-619.   Published online June 15, 2001
Purpose : The National Medical Center has been conducting a study as a Poison Control Center since 1998. The data was analyzed to illustrate the general aspects of acute poisoning in Korean children. Methods : The primary sources of data were collected from the Medical Insurance Records of 1997 and death records of the same period obtained from the Korea National Statistical Office. A total...
Case Report
A Case of Acute Renal Failure Associated with Tsutsugamushi Disease
Jin Hee Hong, Jin Hee Oho, Jong Hyun Kim, Dae Kyun Kho
Clin Exp Pediatr. 2001;44(4):464-468.   Published online April 15, 2001
Tsutsugamushi disease is acute febrile illness, transmitted by Rickettsia tsutsugamushi. R. tsutusgamushi invade and proliferate in the endothelial cells of small blood vessels. Destruction of endothelial cells occurs from the proliferation of the organism and eventual disruption, and thus vascular rich organs must be carefully examined such as the kidney, lung, heart, liver. Recently we experienced a case of acute...
Original Article
Risk Factors of Renal Scar After Acute Pyelonephritis in Children
Chur Woo You
Clin Exp Pediatr. 2001;44(1):54-61.   Published online January 15, 2001
Purpose : In this study we re-evaluated the known risk factors of pyelonephritic scarring in children. Methods : A prospective study was performed on 36 acute pyelonephritis(APN) patients who were diagnosed as first acute pyelonephritis on 99mTc-DMSA scan between September 1998 and March 2000 in Masan Samsung Hospital. According to the prescence of remnant lesions on the 99mTc-DMSA scan performed...
Clinical Application of Impedance Audiometry in Children with Acute Otitis Media
Jee Sung Hwang, Sung Do Kim, Young-Ho Rah, Chong-Woo Bae
Clin Exp Pediatr. 2000;43(11):1446-1450.   Published online November 15, 2000
Purpose : Acute otitis media is one of the most prevalent diseases of childhood and can cause serious complications such as hearing loss. The exact diagnosis is extremely important but may be hard to make because of probabilities of over- and underdiagnosis. We performed impedance audiometry(IA) in routine examinations for acute otitis media and applied it for screening and follow-up...
Case Report
A Recurred Case of Subacute Necrotizing Lymphadenitis(Kikuchi`s Disease) During Childhood
Jin Sun Park, Chang Hee Oh, Je Woo Kim, Phil Soo Oh, Young Ah Lee, He Sun Yun, Jung Weon Shim
Clin Exp Pediatr. 2000;43(9):1285-1289.   Published online September 15, 2000
Subacute necrotizing lymphadenitis, or Kikuchi`s disease, primarily affects the cervical lymph nodes of young adults and has a self-limited clinical course. Differential diagnoses are malignant lymphoma and systemic lupus erythematosus. Recurrence rate is low as 3.3%, and there have been a few reports describing the recurrence of the disease. The symptoms in almost all recurrent cases were similar to those...
Original Article
A Clinical Study of Acute Symptomatic Seizures in Children
Kyeong Eun Lee, Won Seop Kim
Clin Exp Pediatr. 2000;43(9):1254-1262.   Published online September 15, 2000
Purpose : To determine the incidence, etiology, sex, age, seizure type and prognosis of acute symptomatic seizures in children and evaluate the hypothesis that acute symptomatic status epilepticus( SE) is associated with an increased risk of subsequent unprovoked seizure compared with the risk of acute symptomatic seizure without SE. Methods : Five hundred and sixty-eight convulsive children visited the Pediatric Department of Chungbuk National University...
Case Report
A Case of Relapsed Acute Promyleocytic Leukemia Induced Remission with Arsenic Trioxide(As2O3)
Jin Hye Park, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2000;43(8):1132-1136.   Published online August 15, 2000
Acute promyelocytic leukemia(APL) is a unique entity in the spectrum of acute myelogenous leukemia. It has several characteristic features, including distinctive morphology, chromosomal translocation, t(15:17), disseminated intravascular coagulation and effect on retinoic acid. Retinoic acid which is a derivative of vitamin A induces differentation of APL cells in vitro and in vivo, but its cessation induces relapse of APL. Arsenic...
A Case of T-cell Acute Lymphoblastic Leukemia presented with Spontaneous Tumor Lysis Syndrome and Superior Vena Cava Syndrome
Eun Jung Shim, Hyun-Sang Cho, Jae Kook Cha, Jae Kook Cha, Chong Young Park
Clin Exp Pediatr. 2000;43(7):974-977.   Published online July 15, 2000
Acute spontaneous tumor lysis syndrome is a condition resulting from the rapid release of cellular breakdown products into the circulation due to massive cytolysis occurring before start of treatment. It occurs most often in Burkitt' s lymphoma and T-cell ALL, both of which have been well described, following cytotoxic chemotherpy and other single agent administrations. However, only a handful of spontaneous acute tumor lysis...
Original Article
A Study of Clinical Features of Acute Tumor Lysis Syndrome in Children
Ick-Jin Song, Young-Tak Lim
Clin Exp Pediatr. 2000;43(7):952-958.   Published online July 15, 2000
Purpose : Tumor lysis syndrome is characterized by hyperuricemia, hyperphosphatemia, hyperkalemia and hypocalcemia due to destruction of tumor cells. The purpose of this study is to estimate in children the incidence, onset time, differences in outcomes between hemodialysis and conservative therapy, and predictive factor of tumor lysis syndrome before treatment with chemotherapy. Methods : Subjects were 108 children who had received...
Clinical Manifestation of Childhood Acute Leukemia with Bone Involvement
Kyoung Eun Jeong, Hee Jung Lee, Kwang Soon Song, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2000;43(6):806-813.   Published online June 15, 2000
Purpose : Bone involvement is known to develop in 40-70% of pediatric acute leukemia. We aimed to analyze the clinical course and result of therapy in pediatric acute leukemia with bone involvement. Methods : Twenty-seven patients diagnosed as pediatric acute leukemia at Dong San Medical Center from Jan. 1996 to Aug. 1998 were evaluated. According to bone X-ray and whole body...
Case Report
A Case of Acute Renal Failure Following Intravenous Immunoglobulin Therapy in a Child
Sung-Wook Park, Kyung-Yil Lee, Kyung-Yil Lee, Kye-Nam Yoon, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Kyung-Tai Whang
Clin Exp Pediatr. 2000;43(5):720-724.   Published online May 15, 2000
Intravenous immunoglobulin(IVIG) therapy is associated with a number of complications, including rare acute renal failure(ARF). Although the cause of IVIG-associated ARF is unknown, it may be related to the stabilizing agent used in IVIG preparations. ARF following IVIG infusion has not been previously described in children. We report a 4-year-old girl with Kawasaki disease who suffered from ARF following IVIG...
Original Article
Changes in the Findings of 99mTc-dimercaptosuccinic Acid(DMSA) Scan after Acute Pyelonephritis in Childhood and Renal Scar
Sang Hee Ahn, So Young Yoon, Chong Hyun Yoon, Dae Hyuk Moon, Young Seo Park
Clin Exp Pediatr. 2000;43(4):543-549.   Published online April 15, 2000
Purpose : We evaluated the change in the findings of DMSA scan after acute pyelonephritis (APN), and the relationship between renal scar formation and risk factors such as vesicoureteral reflux(VUR), organism and inflammatory reaction. Methods : We examined 200 patients under the age of 5 years with first APN. DMSA scan, voiding cystourethrography(VCUG), erythrocyte sedimentation rate(ESR) and C-reactive protein (CRP) were...
Case Report
Three Cases of Subacute Necrotizing Lymphadenitis in Childhood
Min Hyang Park, Jin A Son, Jae Wook Go, Jae Yoon Kim, Don Hee Ahn
Clin Exp Pediatr. 2000;43(3):423-427.   Published online March 15, 2000
Subacute necrotizing lymphadenitis was first reported by Kikuchi and Fujimoto in 1972. Young females no more than 30 years of age are mainly affected. It usually manifests as fever and cervical lymphadenopathy. We experienced three cases of subacute necrotizing lymphadenitis in an 11-year-old boy, a 12- year-old boy and an 11-year-old girl. Symptoms presented were URI signs, diarrhea, headache and...
Original Article
Anticancer Effect of Arsenic Trioxide in Acute Promyelocytic Leukemia
Ki Young Song, Jin Hye Park, Yoon Jung Cho, Won Ki Baek, Ki Young Kwon, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2000;43(3):327-334.   Published online March 15, 2000
Purpose : Acute promyelocytic leukemia(APL or AML, M3) represents an unique model for cancer research in terms of biological and clinical features. Since 1988, it has been widely confirmed that all-trans retinoic acid(ATRA) can induce complete clinical remission in over 85% of APL patients by a differentiation process, with PML-RARα protein possibly being the direct target of ATRA. However, ATRA...
Clinicial Observations of Oliguric Acute Renal Failure in Children
Sung-Soo Lee, Young-Mi Choi, Chong-Woo Bae, Sung-Ho Cha, Byoung-Soo Cho
Clin Exp Pediatr. 1999;42(10):1419-1425.   Published online October 15, 1999
Purposes : We studied the clinicial findings of oliguric acute renal failure(ARF) developed on admission or during treatment of other diseases. Methods : We performed a retrospective analysis of medical records of 118 patients with oliguric ARF who had been admitted to Kyunghee University Hospital since January 1988 to December 1997. Diagnostic criteria of oliguric ARF are serum creatinine>1.0mg/dl and urine...
Clinical Trends in Acute Rheumatic Fever in Korean Children : Mailed Questionnaire Survey from 1988 to 1997 (Compared with 1978-1987)
Hyeon-Ho Kang, Sung-Ho Cha, Kyong-Su Lee, Sang-Bum Lee, Tae-Chan Kwon, Young-Chang Tockgo, Chang-Sung Son, Jin-A Son, Hee-Ju Park, Yong-Soo Yun, Jung-Yun Choi, Chang-Hwi Kim, Chul-Ho Kim, Tai-Ju Hwang, Jae-Sook Ma, Chan-Uhng Joo, Nam-Su Kim
Clin Exp Pediatr. 1999;42(10):1381-1391.   Published online October 15, 1999
Purpose : The purpose of this study was to assess the frequency of acute rheumatic fever(ARF) among children in Korea and to describe trends in its clinical characteristics compared to data from a previous study(1978-1987). Methods : A mailed questionnaire survey sent to the pediatric departments of 13 general hospitals in Korea requested the total number of patients with ARF and...
Case Report
A Case of Guillain-Barré Syndrome Coinciding with Bronchial Asthma associated with Mycoplasma Pneumonia
Kyung-Yil Lee, Dong-Joon Lee, Ji-Whan Han, Sang-Won Ch, John-Sung Lee, Kyung-Tai Whang
Clin Exp Pediatr. 1999;42(8):1165-1169.   Published online August 15, 1999
Mycoplasma pneumoniae is the most common etiologic agent of pneumonia in school-aged children and young adults. It involves not only the respiratory system but includes extrapulmonary complications such as exanthem, hemolysis, arthritis, hepatic dysfuction, cardiac disease, and central nervous system disease. The pathogenesis of extrapulmonary involvements may be an autoimmune phenomena. Recent studies suggest that bronchial asthma can be initiated...
Original Article
The Risk Factors of Renal Scar in Childhood Acute Pyelonephritis
Soo Ja Hwang, Seung Joo Lee
Clin Exp Pediatr. 1999;42(4):545-552.   Published online April 15, 1999
Purpose : To observe the risk factors of renal scar in children with first acute pyelonephritis (APN) who had photopenic defects on initial 99mTc-DMSA spect renal scan. Methods : Forty-seven children with first APN(M : F=33 : 14) who were admitted to Ewha Womans University Hospital from September, 1993 to Febrary, 1998, were divided into renal scar group(N=17, Kidney unit(KU)=18) and...
Treatment Outcomes in Children with High-Risk Acute Lymphoblastic Leukemia
Kyu Chang Park, Ho Joon Im, Sang Yun Ahn, Hahng Lee
Clin Exp Pediatr. 1999;42(3):383-389.   Published online March 15, 1999
Purpose : The survival rate of those with acute lymphoblastic leukemia(ALL) has been affected by several prognostic factors and previous reports show that a 4-year event-free survival(EFS) for high-risk(HR) group(Age≥10 years and/or WBC≥50,000/mm3 at diagnosis) was approximately 64%. We analyzed treatment outcomes and risk factors in HR-ALL. Methods : Medical records of 27 patients with HR-ALL diagnosed between May, 1985 and...
Clinical Significance of CD7 Expression in Acute Myelocytic Leukemia
Gye Jin Yoon, Pill Sang Jang, Young Choi, Jun A Lee, Hyo Jung Han, Hyoung Soo Choi, Hee Young Shin, Joong Gon Kim, Hyo Seop Ahn
Clin Exp Pediatr. 1999;42(3):374-382.   Published online March 15, 1999
Purpose : It has been shown that a considerable number of acute myeloid leukemia(AML) patients had both myeloid and lymphoid antigens. CD7 is a lymphoid antigen, often expressed in AML cells. We investigated 40 AML patients to clarify the relationship between the cellular characteristics and clinical features. Methods : We reviewed 8 CD7 positive(CD7＋) AML patients and 32 CD7 negative(CD7－)...
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