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Original Article

QT Dispersion after Chemotherapy with Anthracyclines in Children

Jae Kon Ko, Young Hwee Kim, In Sook Park, Jong Jin Seo, Hyung Nam Moon

Clin Exp Pediatr. 2001;44(8):908-915. Published online August 15, 2001

Purpose : Anthracycline induced cardiotoxicity is well known and its pathology is characterized by localized myocardial cell necrosis and myocardial fibrosis. The variability in QT interval duration amongst the different leads of the standard 12-lead ECG(QT dispersion) is considered to reflect inhomogenous repolarization of the myocardium. The aim of this study was to assess the effects of anthracycline on cardiac...

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