Clinical and Experimental Pediatrics

Search

Page Path

HOME
Search

Review Article

Gastroenterology

Patient-derived intestinal organoids in pediatric inflammatory bowel disease: applications in disease modeling and therapeutic response prediction

Ky Young Cho

Clin Exp Pediatr. 2026;69(10):753-761. Published online September 1, 2026

· Patient-derived intestinal organoids provide a human-relevant platform for studying disease mechanisms and evaluating therapeutic responses in pediatric inflammatory bowel disease (PIBD).
· By preserving patient-specific epithelial characteristics, these models enable the functional assessment of disease heterogeneity and drug responsiveness.
· Although technical and biological limitations remain, ongoing advances in immune-inclusive and microphysiological systems are expected to enhance their translational value and support personalized treatment strategies for PIBD.

DOI: https://doi.org/10.3345/cep.2026.00913

Allergy

Action-plan and as-needed therapy in allergic rhinitis

Hyeon-Jong Yang

Clin Exp Pediatr. 2024;67(6):267-273. Published online May 21, 2024

Web of Science 6 Crossref 5

· The guidelines may not work in the real world.
· An action-plan reflecting patient’s severity and variable of symptoms, values and preferences as well as the benefits and harms of treatment, may be a useful alternative.
· The action plan and as-needed therapy must include the following elements: when, what, how, and why.
· Action plan and as-needed therapy can help patients manage their symptoms more effectively.

DOI: https://doi.org/10.3345/cep.2023.00654

MOST CITED ACCEPTED ARTICLES

Cited By 70	Prevalence of anxiety, depression, and stress among parents of neonates admitted to neonatal intensive care unit: a systematic review and meta-analysis
Cited By 42	Community-acquired pneumonia in children: updated perspectives on its etiology, diagnosis, and treatment
Cited By 42	Metabolic complications of obesity in children and adolescents
Cited By 40	Global burden of asthma among children and adolescents with projections to 2050: a comprehensive review and forecasted modeling study
Cited By 39	Neonatal family-centered care: evidence and practice models

+more

Changes in patient concentration and accessibility across 5 Pediatric Emergency Departments in Daegu, Korea

Hematological alterations in adolescent girls with restrictive anorexia nervosa and secondary amenorrhea at the time of diagnosis

Hepcidin and other obesity-related factors affecting BNT162b2 response in children and adolescents over a 6-month period

Association between surgical repair timing and mortality in neonates with congenital diaphragmatic hernia: a systematic review and meta-analysis

Atherogenic lipid profile changes and their cardiovascular consequences across degrees of obesity in children and adolescents: a structured narrative review

+more

ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES

FOR CONTRIBUTORS

ABOUT

Editorial Office: Korean Pediatric Society
#1606 Seocho World Officetel, 19 Seoun-ro, Seocho-ku, Seoul 06732, Korea
Tel: +82-2-3473-7306 Fax: +82-2-3473-7307 E-mail: office@e-cep.org

Clinical and Experimental Pediatrics is an open access journal. All articles are distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/)