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Original Article

Increased vascular endothelial growth factor in children with acute Mycoplasma pneumoniae pneumonia and wheezing

Young Seo, Byung Keun Yu, Yeon Joung Oh, Yoon Lee, Young Yoo, Ji Tae Choung, Young Yull Koh

Clin Exp Pediatr. 2008;51(5):487-491. Published online May 15, 2008

Purpose : Although Mycoplasma pneumoniae (M. pneumoniae) infection can cause wheezing in non-asthmatic children, the mechanisms of this symptom remain unclear. Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis and vascular permeability, and is also known to be elevated in cases of chronic pulmonary disease such as asthma. We hypothesized that VEGF may increase in children with...

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